Chronic inflammatory demyelinative polyneuropathy

Gérard Said, Christian Krarup

20 Citationer (Scopus)

Abstract

Chronic inflammatory demyelinative polyneuropathy (CIDP) is an acquired polyneuropathy presumably of immunological origin. It is characterized by a progressive or a relapsing course with predominant motor deficit. The diagnosis rests on the association of non-length-dependent predominantly motor deficit following a progressive or a relapsing course associated with increased CSF protein content. The demonstration of asymmetrical demyelinating features on nerve conduction studies is needed for diagnosis. The outcome depends on the amplitude of axon loss associated with demyelination. CIDP must be differentiated from acquired demyelinative neuropathies associated with monoclonal gammopathies. CIDP responds well to treatment with corticosteroids, intravenous immunoglobulins, and plasma exchanges, at least initially.
OriginalsprogEngelsk
BogserieHandbook of Clinical Neurology
Vol/bind115
Sider (fra-til)403-13
Antal sider11
ISSN0072-9752
DOI
StatusUdgivet - 2013

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