Chemotherapy induced pathologic complete response in malignant pleural mesothelioma: a review and case report

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    Abstrakt

    Malignant pleural mesothelioma is a rare aggressive disease with a poor prognosis and usually modest responses to chemotherapy. Complete responses (CRs) to chemotherapy are rare. Evaluation is usually based on radiology, and CR is therefore clinical CR (cCR) and whether this indicates absence of viable tumor cells is unknown. We have observed two cases of CR which at subsequent surgery were histologically verified, thus being pathologic CRs (pCRs). pCR after chemotherapy is thus possible but rare, and we here present the cases from our institution together with a review on the literature available on the subject.
    OriginalsprogEngelsk
    TidsskriftJournal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
    Vol/bind5
    Udgave nummer5
    Sider (fra-til)735-40
    Antal sider6
    StatusUdgivet - 1 maj 2010

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