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Characteristics, management and outcomes of very preterm triplets in 19 European regions

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@article{d168e290da5840319ed8f23f86a52049,
title = "Characteristics, management and outcomes of very preterm triplets in 19 European regions",
abstract = "OBJECTIVE: To describe obstetrical care and in-hospital outcomes in very preterm triplet pregnancies in a European multiregional cohort.METHODS: Data from a prospective population-based study of very preterm births between 22+0 and 31+6 weeks of gestation in 19 regions from 11 European countries participating in the EPICE project in 2011/2012 were used to describe triplet pregnancies and compare them with twins and singletons.RESULTS: Triplets constituted 1.1{\%} of very preterm pregnancies (97/8851) and 3.3{\%} of very preterm live births (258/7900); these percentages varied from 0{\%} to 2.6{\%} and 0{\%} to 6{\%} respectively across the regions. In-hospital mortality after live birth was 12.4{\%} and did not differ significantly from singletons or twins or by birth order. However, 28.9{\%} of mothers with a triplet pregnancy experienced at least one neonatal death. Ninety percent of live-born triplets were delivered by cesarean. Vaginal delivery was associated with an Apgar score of less than 7, but not with in-hospital mortality.CONCLUSIONS: The prevalence of very preterm triplets varies across European regions. Most triplets were born by cesarean and those born vaginally had lower Apgar scores. Overall, in-hospital mortality after live birth was similar to singletons and twins. This article is protected by copyright. All rights reserved.",
keywords = "Cesarean section, Fetal growth restriction, In-hospital mortality, Neonatal morbidity, Stillbirth, Triplets, Very preterm birth",
author = "Dudenhausen, {Joachim W} and Bj{\"o}rn Misselwitz and Aurelie Piedvache and Maier, {Rolf F} and Tom Weber and Jennifer Zeitlin and Stephan Schmidt and {EPICE Research Group}",
note = "{\circledC} 2019 International Federation of Gynecology and Obstetrics.",
year = "2019",
month = "12",
doi = "10.1002/ijgo.12939",
language = "English",
volume = "147",
pages = "397--403",
journal = "International Journal of Gynecology and Obstetrics",
issn = "0020-7292",
publisher = "Elsevier Ireland Ltd",
number = "3",

}

RIS

TY - JOUR

T1 - Characteristics, management and outcomes of very preterm triplets in 19 European regions

AU - Dudenhausen, Joachim W

AU - Misselwitz, Björn

AU - Piedvache, Aurelie

AU - Maier, Rolf F

AU - Weber, Tom

AU - Zeitlin, Jennifer

AU - Schmidt, Stephan

AU - EPICE Research Group

N1 - © 2019 International Federation of Gynecology and Obstetrics.

PY - 2019/12

Y1 - 2019/12

N2 - OBJECTIVE: To describe obstetrical care and in-hospital outcomes in very preterm triplet pregnancies in a European multiregional cohort.METHODS: Data from a prospective population-based study of very preterm births between 22+0 and 31+6 weeks of gestation in 19 regions from 11 European countries participating in the EPICE project in 2011/2012 were used to describe triplet pregnancies and compare them with twins and singletons.RESULTS: Triplets constituted 1.1% of very preterm pregnancies (97/8851) and 3.3% of very preterm live births (258/7900); these percentages varied from 0% to 2.6% and 0% to 6% respectively across the regions. In-hospital mortality after live birth was 12.4% and did not differ significantly from singletons or twins or by birth order. However, 28.9% of mothers with a triplet pregnancy experienced at least one neonatal death. Ninety percent of live-born triplets were delivered by cesarean. Vaginal delivery was associated with an Apgar score of less than 7, but not with in-hospital mortality.CONCLUSIONS: The prevalence of very preterm triplets varies across European regions. Most triplets were born by cesarean and those born vaginally had lower Apgar scores. Overall, in-hospital mortality after live birth was similar to singletons and twins. This article is protected by copyright. All rights reserved.

AB - OBJECTIVE: To describe obstetrical care and in-hospital outcomes in very preterm triplet pregnancies in a European multiregional cohort.METHODS: Data from a prospective population-based study of very preterm births between 22+0 and 31+6 weeks of gestation in 19 regions from 11 European countries participating in the EPICE project in 2011/2012 were used to describe triplet pregnancies and compare them with twins and singletons.RESULTS: Triplets constituted 1.1% of very preterm pregnancies (97/8851) and 3.3% of very preterm live births (258/7900); these percentages varied from 0% to 2.6% and 0% to 6% respectively across the regions. In-hospital mortality after live birth was 12.4% and did not differ significantly from singletons or twins or by birth order. However, 28.9% of mothers with a triplet pregnancy experienced at least one neonatal death. Ninety percent of live-born triplets were delivered by cesarean. Vaginal delivery was associated with an Apgar score of less than 7, but not with in-hospital mortality.CONCLUSIONS: The prevalence of very preterm triplets varies across European regions. Most triplets were born by cesarean and those born vaginally had lower Apgar scores. Overall, in-hospital mortality after live birth was similar to singletons and twins. This article is protected by copyright. All rights reserved.

KW - Cesarean section

KW - Fetal growth restriction

KW - In-hospital mortality

KW - Neonatal morbidity

KW - Stillbirth

KW - Triplets

KW - Very preterm birth

UR - http://www.scopus.com/inward/record.url?scp=85073782055&partnerID=8YFLogxK

U2 - 10.1002/ijgo.12939

DO - 10.1002/ijgo.12939

M3 - Journal article

VL - 147

SP - 397

EP - 403

JO - International Journal of Gynecology and Obstetrics

JF - International Journal of Gynecology and Obstetrics

SN - 0020-7292

IS - 3

ER -

ID: 57796393