Abstract
Paracetamol is the most commonly used over-the-counter drug in pregnancy. It is generally considered to be safe, but prolonged antenatal exposure has been associated with offspring short- and long-term morbidity. Our aim was to describe the pattern of paracetamol use with a focus on frequent ingestion (more than once a week), 3 months before and in early pregnancy. In this cohort, 8650 pregnant women responded to a web-based clinical questionnaire that included questions about drug use. Paracetamol was the most used drug before and in early pregnancy (35.2% and 6.5% of respondents, respectively). The proportion of frequent users decreased from 3.9% before to 0.9% in early pregnancy. Frequent paracetamol use was associated with smoking, co-morbidities, body mass index ≥25 kg/m(2) , unplanned pregnancy, no education and inability to understand Danish. A significant decrease in the proportion of women with any paracetamol use in early pregnancy was noted after access to large packs was restricted by legislation.
Originalsprog | Engelsk |
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Tidsskrift | Acta Obstetricia et Gynecologica Scandinavica |
Vol/bind | 94 |
Udgave nummer | 8 |
Sider (fra-til) | 898-903 |
Antal sider | 6 |
ISSN | 0001-6349 |
DOI | |
Status | Udgivet - aug. 2015 |