CGRP receptor antagonist olcegepant (BIBN4096BS) does not prevent glyceryl trinitrate-induced migraine

Jesper Filtenborg Tvedskov; P Tfelt-Hansen; K A Petersen; Lars Thorbjørn Jensen; J Olesen

doi:10.1177/0333102410363491

CGRP receptor antagonist olcegepant (BIBN4096BS) does not prevent glyceryl trinitrate-induced migraine

Jesper Filtenborg Tvedskov, P Tfelt-Hansen, K A Petersen, Lars Thorbjørn Jensen, J Olesen

43 Citationer (Scopus)

Abstract

There is a striking similarity between the migraine-provoking effect of the nitric oxide (NO) donor glyceryl trinitrate (GTN) and that of calcitonin gene-related peptide (CGRP). We tested the hypothesis that NO releases CGRP to cause the delayed migraine attack after GTN.

Originalsprog	Engelsk
Tidsskrift	Cephalalgia
Vol/bind	30
Udgave nummer	11
Sider (fra-til)	1346-53
Antal sider	8
ISSN	0333-1024
DOI	https://doi.org/10.1177/0333102410363491
Status	Udgivet - 1 nov. 2010

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10.1177/0333102410363491

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title = "CGRP receptor antagonist olcegepant (BIBN4096BS) does not prevent glyceryl trinitrate-induced migraine",

abstract = "There is a striking similarity between the migraine-provoking effect of the nitric oxide (NO) donor glyceryl trinitrate (GTN) and that of calcitonin gene-related peptide (CGRP). We tested the hypothesis that NO releases CGRP to cause the delayed migraine attack after GTN.",

author = "Tvedskov, {Jesper Filtenborg} and P Tfelt-Hansen and Petersen, {K A} and Jensen, {Lars Thorbj{\o}rn} and J Olesen",

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T1 - CGRP receptor antagonist olcegepant (BIBN4096BS) does not prevent glyceryl trinitrate-induced migraine

AU - Tvedskov, Jesper Filtenborg

AU - Tfelt-Hansen, P

AU - Petersen, K A

AU - Jensen, Lars Thorbjørn

AU - Olesen, J

PY - 2010/11/1

Y1 - 2010/11/1

N2 - There is a striking similarity between the migraine-provoking effect of the nitric oxide (NO) donor glyceryl trinitrate (GTN) and that of calcitonin gene-related peptide (CGRP). We tested the hypothesis that NO releases CGRP to cause the delayed migraine attack after GTN.

AB - There is a striking similarity between the migraine-provoking effect of the nitric oxide (NO) donor glyceryl trinitrate (GTN) and that of calcitonin gene-related peptide (CGRP). We tested the hypothesis that NO releases CGRP to cause the delayed migraine attack after GTN.

U2 - 10.1177/0333102410363491

DO - 10.1177/0333102410363491

M3 - Journal article

C2 - 20959429

SN - 0333-1024

VL - 30

SP - 1346

EP - 1353

JO - Cephalalgia

JF - Cephalalgia

IS - 11

ER -

CGRP receptor antagonist olcegepant (BIBN4096BS) does not prevent glyceryl trinitrate-induced migraine

Abstract

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