Cerebrospinal fluid CXCL13 in multiple sclerosis: a suggestive prognostic marker for the disease course

Mohsen Khademi; Ingrid Kockum; Magnus L Andersson; Ellen Iacobaeus; Lou Brundin; Finn Sellebjerg; Jan Hillert; Fredrik Piehl; Tomas Olsson

doi:10.1177/1352458510389102

Cerebrospinal fluid CXCL13 in multiple sclerosis: a suggestive prognostic marker for the disease course

Mohsen Khademi, Ingrid Kockum, Magnus L Andersson, Ellen Iacobaeus, Lou Brundin, Finn Sellebjerg, Jan Hillert, Fredrik Piehl, Tomas Olsson

Afdeling for Hjerne- og Nervesygdomme NEU

230 Citationer (Scopus)

Abstract

Levels of CXCL13, a potent B-cell chemoattractant, are elevated in the cerebrospinal fluid (CSF) during multiple sclerosis (MS) and are associated with markers of MS activity. Levels decrease upon effective treatments.

Originalsprog	Engelsk
Tidsskrift	Multiple Sclerosis
Vol/bind	17
Udgave nummer	3
Sider (fra-til)	335-43
Antal sider	9
ISSN	1352-4585
DOI	https://doi.org/10.1177/1352458510389102
Status	Udgivet - 2011

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title = "Cerebrospinal fluid CXCL13 in multiple sclerosis: a suggestive prognostic marker for the disease course",

abstract = "Levels of CXCL13, a potent B-cell chemoattractant, are elevated in the cerebrospinal fluid (CSF) during multiple sclerosis (MS) and are associated with markers of MS activity. Levels decrease upon effective treatments.",

keywords = "Adolescent, Adult, Aged, Biological Markers, Chemokine CXCL13, Demyelinating Diseases, Disability Evaluation, Disease Progression, Enzyme-Linked Immunosorbent Assay, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Multiple Sclerosis, Chronic Progressive, Multiple Sclerosis, Relapsing-Remitting, Oligoclonal Bands, Predictive Value of Tests, Prognosis, Reproducibility of Results, Sweden, Time Factors, Up-Regulation, Young Adult",

author = "Mohsen Khademi and Ingrid Kockum and Andersson, \{Magnus L\} and Ellen Iacobaeus and Lou Brundin and Finn Sellebjerg and Jan Hillert and Fredrik Piehl and Tomas Olsson",

year = "2011",

doi = "10.1177/1352458510389102",

language = "English",

volume = "17",

pages = "335--43",

journal = "Multiple Sclerosis",

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T1 - Cerebrospinal fluid CXCL13 in multiple sclerosis: a suggestive prognostic marker for the disease course

AU - Khademi, Mohsen

AU - Kockum, Ingrid

AU - Andersson, Magnus L

AU - Iacobaeus, Ellen

AU - Brundin, Lou

AU - Sellebjerg, Finn

AU - Hillert, Jan

AU - Piehl, Fredrik

AU - Olsson, Tomas

PY - 2011

Y1 - 2011

N2 - Levels of CXCL13, a potent B-cell chemoattractant, are elevated in the cerebrospinal fluid (CSF) during multiple sclerosis (MS) and are associated with markers of MS activity. Levels decrease upon effective treatments.

AB - Levels of CXCL13, a potent B-cell chemoattractant, are elevated in the cerebrospinal fluid (CSF) during multiple sclerosis (MS) and are associated with markers of MS activity. Levels decrease upon effective treatments.

KW - Adolescent

KW - Adult

KW - Aged

KW - Biological Markers

KW - Chemokine CXCL13

KW - Demyelinating Diseases

KW - Disability Evaluation

KW - Disease Progression

KW - Enzyme-Linked Immunosorbent Assay

KW - Female

KW - Humans

KW - Magnetic Resonance Imaging

KW - Male

KW - Middle Aged

KW - Multiple Sclerosis, Chronic Progressive

KW - Multiple Sclerosis, Relapsing-Remitting

KW - Oligoclonal Bands

KW - Predictive Value of Tests

KW - Prognosis

KW - Reproducibility of Results

KW - Sweden

KW - Time Factors

KW - Up-Regulation

KW - Young Adult

UR - https://www.scopus.com/pages/publications/79953179371

U2 - 10.1177/1352458510389102

DO - 10.1177/1352458510389102

M3 - Journal article

C2 - 21135023

SN - 1352-4585

VL - 17

SP - 335

EP - 343

JO - Multiple Sclerosis

JF - Multiple Sclerosis

IS - 3

ER -

Cerebrospinal fluid CXCL13 in multiple sclerosis: a suggestive prognostic marker for the disease course

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