@article{f25e2102d0b94d67bf5d67d085b66109,
title = "Cerebral sinus venous thromboses in children with acute lymphoblastic leukaemia - a multicentre study from the Nordic Society of Paediatric Haematology and Oncology",
abstract = "We present a prospective multicentre cohort of 20 children with acute lymphoblastic leukaemia (ALL) and cerebral sinus venous thrombosis (CSVT). The study covers a period of 5 years and comprises 1038 children treated according to the Nordic Society of Paediatric Haematology and Oncology (NOPHO) ALL 2008 protocol. The cumulative incidence of CSVT was 2%. Sixteen of the thromboses were related to asparaginase and 16 to steroids. Most CSVTs occurred in the consolidation phase. Nearly all were treated with low molecular weight heparin without bleeding complications. Mortality related to CSVT directly or indirectly was 10%, emphasizing the importance of this complication.",
keywords = "Adolescent, Adrenal Cortex Hormones, Anticoagulants, Antineoplastic Combined Chemotherapy Protocols, Asparaginase, Baltic States, Child, Child, Preschool, Consolidation Chemotherapy, Female, Humans, Incidence, Infant, Male, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Prospective Studies, Risk Factors, Scandinavian and Nordic Countries, Sinus Thrombosis, Intracranial, Treatment Outcome",
author = "Susanna Ranta and Ruta Tuckuviene and Anne M{\"a}kipernaa and Albertsen, {Birgitte K} and Tony Frisk and Ulf Tedg{\aa}rd and J{\'o}nsson, {{\'O}lafur G} and Kaie Pruunsild and {Gretenkort Andersson}, Nadine and {Winther Gunnes}, Maria and {Saulyte Trakymiene}, Sonata and Thomas Frandsen and Mats Heyman and Ellen Ruud and Jon Helgestad",
note = "{\textcopyright} 2014 John Wiley & Sons Ltd.",
year = "2015",
month = feb,
doi = "10.1111/bjh.13162",
language = "English",
volume = "168",
pages = "547--52",
journal = "British Journal of Haematology",
issn = "0007-1048",
publisher = "Wiley-Blackwell Publishing Ltd",
number = "4",
}