Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Causes and outcomes of hospitalizations among people living with HIV in Georgia's referral institution, 2012-2017

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. HIV pre-test information, discussion or counselling? A review of guidance relevant to the WHO European Region

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  2. Encephalitis in primary HIV infection: challenges in diagnosis and treatment

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Prevalence of sexually transmitted infections among women attending antenatal clinics in Tanga, north eastern Tanzania

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Anogenital warts in Danish men who have sex with men

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Incidence and impact of parvovirus B19 infection in seronegative solid organ transplant recipients

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Response to Aviv et al

    Publikation: Bidrag til tidsskriftLetterForskningpeer review

  3. Hydroxychloroquine as a primary prophylactic agent against sars-cov-2 infection: a cohort study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  • Nino Rukhadze
  • Ole Kirk
  • Nikoloz Chkhartishvili
  • Natalia Bolokadze
  • Lali Sharvadze
  • Pati Gabunia
  • Jens Lundgren
  • Tengiz Tsertsvadze
Vis graf over relationer

We assessed trends in causes and outcomes of hospitalization among people living with HIV (PLWH) admitted to the Infectious Diseases, AIDS and Clinical Immunology Research Center (IDACIRC) in Tbilisi, Georgia. Retrospective analysis included adult PLWH admitted to IDACIRC for at least 24 h. Internationally validated categorization was used to split AIDS admissions into mild, moderate, and severe AIDS. A total of 2085 hospitalizations among 1123 PLWH were registered over 2012-2017 with 65.1% (731/1123) of patients presenting with CD4 count <200. Of 2085 hospitalizations, 931 (44.7%) were due to AIDS-defining illnesses. In 2012, AIDS conditions accounted for 50.3% of admissions compared to 41.6% in 2017 (p = 0.16). Overall, 167 hospitalizations (8.0%) resulted in lethal outcome. AIDS admissions had higher mortality than non-AIDS admissions (11.5% vs 5.2%, p < 0.0001). Among 167 deceased patients, 137 (82.0%) had CD4 count <200 at admission. In multivariate analysis, factors significantly associated with mortality included severe AIDS versus non-AIDS admission (OR 2.81, 95% CI: 1.10-7.15), CD4 cell counts <50 (OR 4.34, 95% CI: 2.52-7.47), and 50-100 (OR 2.37, 95% CI: 1.27-4.42) versus >200. Active AIDS disease remains a significant cause of hospitalization and fatal outcome in Georgia. Earlier diagnosis of HIV is critical for decreasing AIDS hospitalizations and mortality.

OriginalsprogEngelsk
TidsskriftInternational Journal of STD and AIDS
Vol/bind32
Udgave nummer7
Sider (fra-til)662-670
Antal sider9
ISSN0956-4624
DOI
StatusUdgivet - jun. 2021

ID: 64031239