Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Categorization of changes in the Oxford Knee Score after Total Knee Replacement: An interpretive tool developed from a dataset of 46,094 replacements

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. GRADE guidelines 32: GRADE offers guidance on choosing targets of GRADE certainty of evidence ratings

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Validation studies in epidemiologic research: Estimation of the positive predictive value

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Effect Modifiers and Statistical Tests for Interaction in Randomized Trials

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Evidence-Based Research Series-Paper 1: What Evidence-Based Research is and why is it important?

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Evidence-Based Research Series-Paper 2: Using an Evidence-Based Research approach before a new study is conducted to ensure value

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

OBJECTIVES: The objective of the study was to create an interpretive categorical classification for the transition in the Oxford Knee Score (OKS) change score (ΔOKS) using the anchor-based method.

STUDY DESIGN AND SETTING: Registry data from 46,094 total knee replacements from the year 2014/15, were accessed via the Health and Social Care Information Center official website. Data included preoperative and 6-month follow-up OKS and response to the transition anchor question. Categories were determined using Gaussian approximation probability and k-fold cross-validation.

RESULTS: Four categories were identified with the corresponding ΔOKS intervals: "1. much better" (≥16), "2. a little better" (7-15), "3. about the same" (1-6), and "4. much worse" (≤0) based on the anchor questions' original five categories. The mean 10-fold cross-validation error was 0.35 OKS points (95% confidence interval 0.12 to 0.63). Sensitivity ranged from 0.34 to 0.68; specificity ranged from 0.74 to 0.95.

CONCLUSION: We have categorized the change score into a clinically meaningful classification. We argue it should be an addition to the continuous OKS outcome to contextualize the results in a way more applicable to the shared decision-making process and for interpreting research results.

OriginalsprogEngelsk
TidsskriftJournal of Clinical Epidemiology
Vol/bind132
Sider (fra-til)18-25
Antal sider8
ISSN0895-4356
DOI
StatusUdgivet - 1 apr. 2021

ID: 61502301