@article{955d0102332140208e53ab29ea7925ee,
title = "CASP8 D302H and meningioma risk: an analysis of five case-control series",
abstract = "Caspase 8 (CASP8) is a key regulator of apoptosis or programmed cell death, and hence a defence against cancer. The CASP8 polymorphism D302H has recently been shown to influence the risk of breast cancer. We tested the hypothesis that the CASP8 polymorphism D302H may influence risk of meningioma through analysis of five independent series of case patients and controls (n=631 and 637, respectively). Carrier status for 302H was not associated with a statistically significantly increased risk (OR=1.16; 95% CI: 0.87-1.53; P=0.31) making it unlikely that this variant contributes to the inherited risk of meningioma.",
keywords = "Adult, Aged, Alleles, Apoptosis, Case-Control Studies, Caspase 8/genetics, Female, Genetic Variation, Humans, Male, Meningeal Neoplasms/genetics, Meningioma/diagnosis, Middle Aged, Polymorphism, Genetic, Risk",
author = "Lara Bethke and Kate Sullivan and Emily Webb and Anne Murray and Minouk Schoemaker and Anssi Auvinen and Anne Kiuru and Tiina Salminen and Christoffer Johansen and Christensen, {Helle Collatz} and Kenneth Muir and Patricia McKinney and Sarah Hepworth and Polyxeni Dimitropoulou and Artitaya Lophatananon and Maria Feychting and Stefan L{\"o}nn and Anders Ahlbom and Beatrice Malmer and Roger Henriksson and Anthony Swerdlow and Richard Houlston",
year = "2009",
month = jan,
day = "18",
doi = "10.1016/j.canlet.2008.08.010",
language = "English",
volume = "273",
pages = "312--5",
journal = "Cancer Letters",
issn = "0304-3835",
publisher = "Elsevier Ireland Ltd",
number = "2",
}