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Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Cardiovascular effects of antidiabetic drugs

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Vis graf over relationer

Type 2 diabetes mellitus is a common and severe chronic metabolic disease, which confers increased risk of cardiovascular disease and mortality. During the last decade a large number of new drugs within the classes dipeptidyl peptidase 4 (DPP-4) inhibitors (DPP-4Is), glucagon-like peptide 1 (GLP-1) receptor agonists (GLP-1RAs) and sodium/glucose cotransporter 2 (SGLT-2) inhibitors (SGLT-2Is) have been developed and tested in nine large-scale cardiovascular outcome trials (CVOTs). Here we review the evidence behind antihyperglycemic treatment of patients with type 2 diabetes with a particular focus on compiling and summarizing the evidence of hard clinical endpoints stemming from these large CVOTs.

OriginalsprogEngelsk
TidsskriftDrugs of Today
Vol/bind54
Udgave nummer9
Sider (fra-til)547-559
Antal sider13
ISSN1699-3993
DOI
StatusUdgivet - sep. 2018

ID: 55493831