Cardiac repolarization during hypoglycaemia in type 1 diabetes: impact of basal renin-angiotensin system activity

Rikke Due-Andersen; Thomas Høi-Hansen; Charlotte Ellen Larroude; Niels Vidiendal Olsen; Jørgen Kim Kanters; Frans Boomsma; Ulrik Pedersen-Bjergaard; Birger Thorsteinsson

doi:10.1093/europace/eun137

Cardiac repolarization during hypoglycaemia in type 1 diabetes: impact of basal renin-angiotensin system activity

Rikke Due-Andersen
, Thomas Høi-Hansen
, Charlotte Ellen Larroude
, Niels Vidiendal Olsen
, Jørgen Kim Kanters
, Frans Boomsma
, Ulrik Pedersen-Bjergaard
, Birger Thorsteinsson

14 Citationer (Scopus)

Abstract

Hypoglycaemia-induced cardiac arrhythmias may be involved in the pathogenesis of the 'dead-in-bed syndrome' in patients with type 1 diabetes. Evidence suggests that the renin-angiotensin system (RAS) influences the occurrence of arrhythmias. The aim of this study was to explore if basal RAS activity affects cardiac repolarization during hypoglycaemia, thereby potentially carrying prognostic information on risk of the 'dead-in-bed syndrome'.

Originalsprog	Engelsk
Tidsskrift	Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
Vol/bind	10
Udgave nummer	7
Sider (fra-til)	860-7
Antal sider	8
ISSN	1099-5129
DOI	https://doi.org/10.1093/europace/eun137
Status	Udgivet - jul. 2008

Adgang til dokumentet

10.1093/europace/eun137

Citationsformater

Due-Andersen, R., Høi-Hansen, T., Larroude, C. E., Olsen, N. V., Kanters, J. K., Boomsma, F., Pedersen-Bjergaard, U., & Thorsteinsson, B. (2008). Cardiac repolarization during hypoglycaemia in type 1 diabetes: impact of basal renin-angiotensin system activity. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 10(7), 860-7. https://doi.org/10.1093/europace/eun137

Cardiac repolarization during hypoglycaemia in type 1 diabetes: impact of basal renin-angiotensin system activity. / Due-Andersen, Rikke; Høi-Hansen, Thomas; Larroude, Charlotte Ellen et al.
I: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Bind 10, Nr. 7, 07.2008, s. 860-7.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Due-Andersen, R, Høi-Hansen, T, Larroude, CE, Olsen, NV, Kanters, JK, Boomsma, F, Pedersen-Bjergaard, U & Thorsteinsson, B 2008, 'Cardiac repolarization during hypoglycaemia in type 1 diabetes: impact of basal renin-angiotensin system activity', Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, bind 10, nr. 7, s. 860-7. https://doi.org/10.1093/europace/eun137

Due-Andersen R, Høi-Hansen T, Larroude CE, Olsen NV, Kanters JK, Boomsma F et al. Cardiac repolarization during hypoglycaemia in type 1 diabetes: impact of basal renin-angiotensin system activity. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 2008 jul.;10(7):860-7. doi: 10.1093/europace/eun137

Due-Andersen, Rikke ; Høi-Hansen, Thomas ; Larroude, Charlotte Ellen et al. / Cardiac repolarization during hypoglycaemia in type 1 diabetes : impact of basal renin-angiotensin system activity. I: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 2008 ; Bind 10, Nr. 7. s. 860-7.

@article{d759d91641934e4aaa760cf5f86363ac,

title = "Cardiac repolarization during hypoglycaemia in type 1 diabetes: impact of basal renin-angiotensin system activity",

abstract = "Hypoglycaemia-induced cardiac arrhythmias may be involved in the pathogenesis of the 'dead-in-bed syndrome' in patients with type 1 diabetes. Evidence suggests that the renin-angiotensin system (RAS) influences the occurrence of arrhythmias. The aim of this study was to explore if basal RAS activity affects cardiac repolarization during hypoglycaemia, thereby potentially carrying prognostic information on risk of the 'dead-in-bed syndrome'.",

keywords = "Adult, Blood Glucose, Cross-Over Studies, Death, Sudden, Cardiac, Diabetes Mellitus, Type 1, Electrocardiography, Epinephrine, Female, Heart Rate, Humans, Hypoglycemia, Insulin, Male, Middle Aged, Prognosis, Renin-Angiotensin System, Risk Factors, Single-Blind Method, Tachycardia, Ventricular",

author = "Rikke Due-Andersen and Thomas H{\o}i-Hansen and Larroude, \{Charlotte Ellen\} and Olsen, \{Niels Vidiendal\} and Kanters, \{J{\o}rgen Kim\} and Frans Boomsma and Ulrik Pedersen-Bjergaard and Birger Thorsteinsson",

year = "2008",

month = jul,

doi = "10.1093/europace/eun137",

language = "English",

volume = "10",

pages = "860--7",

journal = "Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology",

issn = "1099-5129",

publisher = "Oxford University Press",

number = "7",

}

TY - JOUR

T1 - Cardiac repolarization during hypoglycaemia in type 1 diabetes

T2 - impact of basal renin-angiotensin system activity

AU - Due-Andersen, Rikke

AU - Høi-Hansen, Thomas

AU - Larroude, Charlotte Ellen

AU - Olsen, Niels Vidiendal

AU - Kanters, Jørgen Kim

AU - Boomsma, Frans

AU - Pedersen-Bjergaard, Ulrik

AU - Thorsteinsson, Birger

PY - 2008/7

Y1 - 2008/7

N2 - Hypoglycaemia-induced cardiac arrhythmias may be involved in the pathogenesis of the 'dead-in-bed syndrome' in patients with type 1 diabetes. Evidence suggests that the renin-angiotensin system (RAS) influences the occurrence of arrhythmias. The aim of this study was to explore if basal RAS activity affects cardiac repolarization during hypoglycaemia, thereby potentially carrying prognostic information on risk of the 'dead-in-bed syndrome'.

AB - Hypoglycaemia-induced cardiac arrhythmias may be involved in the pathogenesis of the 'dead-in-bed syndrome' in patients with type 1 diabetes. Evidence suggests that the renin-angiotensin system (RAS) influences the occurrence of arrhythmias. The aim of this study was to explore if basal RAS activity affects cardiac repolarization during hypoglycaemia, thereby potentially carrying prognostic information on risk of the 'dead-in-bed syndrome'.

KW - Adult

KW - Blood Glucose

KW - Cross-Over Studies

KW - Death, Sudden, Cardiac

KW - Diabetes Mellitus, Type 1

KW - Electrocardiography

KW - Epinephrine

KW - Female

KW - Heart Rate

KW - Humans

KW - Hypoglycemia

KW - Insulin

KW - Male

KW - Middle Aged

KW - Prognosis

KW - Renin-Angiotensin System

KW - Risk Factors

KW - Single-Blind Method

KW - Tachycardia, Ventricular

U2 - 10.1093/europace/eun137

DO - 10.1093/europace/eun137

M3 - Journal article

C2 - 18534966

SN - 1099-5129

VL - 10

SP - 860

EP - 867

JO - Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

JF - Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

IS - 7

ER -

Cardiac repolarization during hypoglycaemia in type 1 diabetes: impact of basal renin-angiotensin system activity

Abstract

Adgang til dokumentet

Fingeraftryk

Citationsformater