Carcinoma in situ of the testis. Some ultrastructural characteristics of germ cells

R Albrechtsen; M H Nielsen; N E Skakkebaek; U Wewer

doi:10.1111/j.1699-0463.1982.tb00097_90a.x

Carcinoma in situ of the testis. Some ultrastructural characteristics of germ cells

R Albrechtsen, M H Nielsen, N E Skakkebaek, U Wewer

Abstrakt

The two cytoplasmic organelles, dense-cored vesicles and "nuages" have been considered to allow positive identification of primordial germ cells in rodents, but no use of these potential markers has been applied to human material. We have observed dense-cored vesicles and "nuages" in the abnormal germ cells of carcinoma in situ of the testis and thus brought further evidence for the germ cell origin of this lesion. These organelles may be useful cytoplasmic markers in the study of germ cell tumors.

Originalsprog	Engelsk
Tidsskrift	Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology
Vol/bind	90
Udgave nummer	4
Sider (fra-til)	301-3
Antal sider	3
ISSN	0108-0164
DOI	https://doi.org/10.1111/j.1699-0463.1982.tb00097_90a.x
Status	Udgivet - jul. 1982
Udgivet eksternt	Ja

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10.1111/j.1699-0463.1982.tb00097_90a.x

Citationsformater

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title = "Carcinoma in situ of the testis. Some ultrastructural characteristics of germ cells",

abstract = "The two cytoplasmic organelles, dense-cored vesicles and {"}nuages{"} have been considered to allow positive identification of primordial germ cells in rodents, but no use of these potential markers has been applied to human material. We have observed dense-cored vesicles and {"}nuages{"} in the abnormal germ cells of carcinoma in situ of the testis and thus brought further evidence for the germ cell origin of this lesion. These organelles may be useful cytoplasmic markers in the study of germ cell tumors.",

keywords = "Adult, Animals, Carcinoma in Situ/ultrastructure, Female, Germ Cells/ultrastructure, Humans, Male, Rats, Rats, Inbred Strains, Testicular Neoplasms/ultrastructure",

author = "R Albrechtsen and Nielsen, {M H} and Skakkebaek, {N E} and U Wewer",

year = "1982",

month = jul,

doi = "10.1111/j.1699-0463.1982.tb00097_90a.x",

language = "English",

volume = "90",

pages = "301--3",

journal = "Acta pathologica et microbiologica Scandinavica",

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TY - JOUR

T1 - Carcinoma in situ of the testis. Some ultrastructural characteristics of germ cells

AU - Albrechtsen, R

AU - Nielsen, M H

AU - Skakkebaek, N E

AU - Wewer, U

PY - 1982/7

Y1 - 1982/7

N2 - The two cytoplasmic organelles, dense-cored vesicles and "nuages" have been considered to allow positive identification of primordial germ cells in rodents, but no use of these potential markers has been applied to human material. We have observed dense-cored vesicles and "nuages" in the abnormal germ cells of carcinoma in situ of the testis and thus brought further evidence for the germ cell origin of this lesion. These organelles may be useful cytoplasmic markers in the study of germ cell tumors.

AB - The two cytoplasmic organelles, dense-cored vesicles and "nuages" have been considered to allow positive identification of primordial germ cells in rodents, but no use of these potential markers has been applied to human material. We have observed dense-cored vesicles and "nuages" in the abnormal germ cells of carcinoma in situ of the testis and thus brought further evidence for the germ cell origin of this lesion. These organelles may be useful cytoplasmic markers in the study of germ cell tumors.

KW - Adult

KW - Animals

KW - Carcinoma in Situ/ultrastructure

KW - Female

KW - Germ Cells/ultrastructure

KW - Humans

KW - Male

KW - Rats

KW - Rats, Inbred Strains

KW - Testicular Neoplasms/ultrastructure

U2 - 10.1111/j.1699-0463.1982.tb00097_90a.x

DO - 10.1111/j.1699-0463.1982.tb00097_90a.x

M3 - Journal article

C2 - 6889804

VL - 90

SP - 301

EP - 303

JO - Acta pathologica et microbiologica Scandinavica

JF - Acta pathologica et microbiologica Scandinavica

SN - 0365-5555

IS - 4

ER -

Carcinoma in situ of the testis. Some ultrastructural characteristics of germ cells

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