Carbonic anhydrase inhibition increases retinal oxygen tension and dilates retinal vessels

Daniella Bach Pedersen, Peter Koch Jensen, Morten la Cour, Jens Folke Kiilgaard, Thor Eysteinsson, Kurt Bang, Anne Wiencke, Einar Stefánsson

56 Citationer (Scopus)

Abstract

Carbonic anhydrase inhibitors (CAIs) increase blood flow in the brain and probably also in the optic nerve and retina. Additionally they elevate the oxygen tension in the optic nerve in the pig. We propose that they also raise the oxygen tension in the retina. We studied the oxygen tension in the pig retina and optic nerve before and after dorzolamide injection. Also the retinal vessel diameters during carbonic anhydrase inhibition were studied.
OriginalsprogEngelsk
TidsskriftGraefe's Archive for Clinical and Experimental Ophthalmology
Vol/bind243
Udgave nummer2
Sider (fra-til)163-8
Antal sider6
ISSN0721-832X
DOI
StatusUdgivet - 2005

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