Capsaicin-induced neurogenic inflammation in the skin in patients with symptoms induced by odorous chemicals

Helle Holst, Lars Arendt-Nielsen, Holger Mosbech, Jørgen Serup, Jesper Elberling

16 Citationer (Scopus)

Abstract

Intradermal injection of capsaicin induces the axonal release of neuropeptides, vasodilatation and flare, e.g. neurogenic inflammation. The spatial profile of neurogenic inflammation in the skin has been studied in various experimental models. Polarization spectroscopy imaging introduced recently may be used for the quantitative assessment of the temporal profile of neurogenic inflammation expressed as erythema intensity.

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