TY - JOUR
T1 - Capecitabine and oxaliplatin as second-line treatment in patients with carcinoma of unknown primary site
AU - Møller, Anne Kirstine Hundahl
AU - Pedersen, Karen Damgaard
AU - Abildgaard, Julie Rafn
AU - Petersen, Bodil Laub
AU - Daugaard, Gedske
PY - 2010/5/1
Y1 - 2010/5/1
N2 - Treatment of patients with carcinoma of unknown primary site (CUP) remains a challenge, and no effective second-line treatment has been identified. In CUP patients who are non-responsive or relapse early after first-line platinum/taxane-based regimens, it is likely that gastrointestinal (GI) tract tumours may be overrepresented. These patients could be candidates for GI tract-directed therapy. We here report the results obtained with oxaliplatin and capecitabine as second-line therapy in 25 recurrent/refractory CUP patients following first-line treatment with paclitaxel, cisplatin and gemcitabine.
AB - Treatment of patients with carcinoma of unknown primary site (CUP) remains a challenge, and no effective second-line treatment has been identified. In CUP patients who are non-responsive or relapse early after first-line platinum/taxane-based regimens, it is likely that gastrointestinal (GI) tract tumours may be overrepresented. These patients could be candidates for GI tract-directed therapy. We here report the results obtained with oxaliplatin and capecitabine as second-line therapy in 25 recurrent/refractory CUP patients following first-line treatment with paclitaxel, cisplatin and gemcitabine.
U2 - 10.3109/02841861003649240
DO - 10.3109/02841861003649240
M3 - Journal article
C2 - 20235750
SN - 0001-6357
VL - 49
SP - 431
EP - 435
JO - Acta Odontologica Scandinavica
JF - Acta Odontologica Scandinavica
IS - 4
ER -