Abstract
BACKGROUND: In the context of the Danish Head and Neck Cancer Group, nationwide material from 1992-2001 was analyzed to study the extent and nature of the disease, evaluate treatment, compare staging systems, and examine prognosis and survival.
METHODS: Review of 68 consecutive cases: 47 squamous cell carcinoma, 10 basal cell carcinoma, and 11 other histologies. Moody (modified Pittsburgh) stages were T1 (26), T2 (9), T3 (8), T4 (23), Tx (2). Sixty-four patients were treated with curative intent: 24 primary radiotherapy, 18 primary surgery, and 22 combined. Surgery was limited to tumor excision and mastoidectomy and in 1 case temporal bone excision.
RESULTS: Twenty-seven of 28 recurrences involved primary site. Kaplan-Meier analysis showed 5-year locoregional control of 48%, disease-specific survival 57%, and overall survival 44%.
CONCLUSION: This nationwide study confirmed that local failure is the main problem, and future improvements should focus on more aggressive local treatment.
Originalsprog | Engelsk |
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Tidsskrift | Head and Neck |
Vol/bind | 30 |
Udgave nummer | 10 |
Sider (fra-til) | 1332-8 |
Antal sider | 7 |
ISSN | 1043-3074 |
DOI | |
Status | Udgivet - okt. 2008 |
Udgivet eksternt | Ja |