TY - JOUR
T1 - Can preoperative brain imaging features predict shunt response in idiopathic normal pressure hydrocephalus?
T2 - A PRISMA review
AU - Carlsen, Jonathan Frederik
AU - Munch, Tina Nørgaard
AU - Hansen, Adam Espe
AU - Hasselbalch, Steen Gregers
AU - Rykkje, Alexander Malcolm
N1 - © 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
PY - 2022/11
Y1 - 2022/11
N2 - PURPOSE: This systematic literature review aimed to identify brain computed tomography (CT) and magnetic resonance imaging (MRI) features that could be used to discriminate idiopathic normal pressure hydrocephalus (iNPH) shunt responders from non-responders.METHODS: PubMed, Embase, Web of Science, and Cochrane were searched following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Only original research articles reporting preoperative CT and/or MRI features and iNPH shunt response evaluated by changes in gait, dementia, and urinary incontinence were included. Title and abstract screening and full-text article evaluation were done by two authors. Data on patient demographics and inclusion criteria, brain image evaluation, shunting methods, and shunt response evaluation were recorded.RESULTS: The search resulted in 1274 studies after removing duplicates. Twenty-seven studies were chosen for final review. Both structural (i.e., callosal angle, disproportionately enlarged subarachnoid space hydrocephalus (DESH), and temporal horn diameter) and physiological brain imaging (including aqueductal flow measurement and brain perfusion) had been examined. Fourteen out of 27 studies found no difference in any assessed imaging parameters between responders and non-responders, and none of the examined imaging parameters was repeatedly and consistently reported as significantly different between the two groups.CONCLUSIONS: No brain imaging parameters were consistently and repeatedly reported as different between iNPH shunt responders and non-responders.
AB - PURPOSE: This systematic literature review aimed to identify brain computed tomography (CT) and magnetic resonance imaging (MRI) features that could be used to discriminate idiopathic normal pressure hydrocephalus (iNPH) shunt responders from non-responders.METHODS: PubMed, Embase, Web of Science, and Cochrane were searched following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Only original research articles reporting preoperative CT and/or MRI features and iNPH shunt response evaluated by changes in gait, dementia, and urinary incontinence were included. Title and abstract screening and full-text article evaluation were done by two authors. Data on patient demographics and inclusion criteria, brain image evaluation, shunting methods, and shunt response evaluation were recorded.RESULTS: The search resulted in 1274 studies after removing duplicates. Twenty-seven studies were chosen for final review. Both structural (i.e., callosal angle, disproportionately enlarged subarachnoid space hydrocephalus (DESH), and temporal horn diameter) and physiological brain imaging (including aqueductal flow measurement and brain perfusion) had been examined. Fourteen out of 27 studies found no difference in any assessed imaging parameters between responders and non-responders, and none of the examined imaging parameters was repeatedly and consistently reported as significantly different between the two groups.CONCLUSIONS: No brain imaging parameters were consistently and repeatedly reported as different between iNPH shunt responders and non-responders.
KW - Idiopathic normal pressure hydrocephalus
KW - Magnetic resonance imaging
KW - Computed tomography
KW - Shunt response
KW - Brain/diagnostic imaging
KW - Subarachnoid Space/pathology
KW - Humans
KW - Corpus Callosum/pathology
KW - Magnetic Resonance Imaging/methods
KW - Hydrocephalus, Normal Pressure/diagnostic imaging
UR - http://www.scopus.com/inward/record.url?scp=85135192274&partnerID=8YFLogxK
U2 - 10.1007/s00234-022-03021-9
DO - 10.1007/s00234-022-03021-9
M3 - Review
C2 - 35871239
SN - 0028-3940
VL - 64
SP - 2119
EP - 2133
JO - Neuroradiology
JF - Neuroradiology
IS - 11
ER -