@article{b512a9abe83c40fd99fef597b82c64a1,
title = "Calpain 3 is important for muscle regeneration: evidence from patients with limb girdle muscular dystrophies",
abstract = "Limb girdle muscular dystrophy (LGMD) type 2A is caused by mutations in the CAPN3 gene and complete lack of functional calpain 3 leads to the most severe muscle wasting. Calpain 3 is suggested to be involved in maturation of contractile elements after muscle degeneration. The aim of this study was to investigate how mutations in the four functional domains of calpain 3 affect muscle regeneration.",
keywords = "Adolescent, Adult, Apoptosis, Biological Markers, Biopsy, Blotting, Western, Calpain, Denmark, Dystrophin, Female, Genetic Predisposition to Disease, Humans, Immunohistochemistry, Linear Models, Male, Middle Aged, Muscle Proteins, Muscle, Skeletal, Muscular Dystrophies, Limb-Girdle, Muscular Dystrophy, Duchenne, Mutation, MyoD Protein, Myogenin, Myosin Heavy Chains, Phenotype, Proteins, Regeneration, Severity of Illness Index, Vimentin, Young Adult",
author = "Simon Hauerslev and Marie-Louise Sveen and Morten Duno and Corrado Angelini and John Vissing and Krag, {Thomas O}",
year = "2012",
doi = "10.1186/1471-2474-13-43",
language = "English",
volume = "13",
pages = "43--53",
journal = "B M C Musculoskeletal Disorders",
issn = "1471-2474",
publisher = "BioMed Central Ltd",
}