Calcitonin gene-related peptide triggers migraine-like attacks in patients with migraine with aura

417 Citationer (Scopus)

Abstract

Calcitonin gene-related peptide (CGRP) is a key molecule in migraine pathogenesis. Intravenous CGRP infusion triggers delayed migraine-like attacks in patients with migraine without aura (MO). In contrast to patients with MO, in prior studies patients with familial hemiplegic migraine (FHM) did not report more migraine-like attacks compared to controls. Whether CGRP triggers migraine in patients with typical (non-hemiplegic) migraine with aura is (MA) unknown. In the present study we examined the migraine inducing effect of CGRP infusion in patients suffering from MA and healthy controls.
OriginalsprogEngelsk
TidsskriftCephalalgia
Vol/bind30
Udgave nummer10
Sider (fra-til)1179-86
Antal sider8
ISSN0333-1024
DOI
StatusUdgivet - 2010

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