Calcitonin gene-related peptide does not cause migraine attacks in patients with familial hemiplegic migraine

Jakob M Hansen; Lise L Thomsen; Jes Olesen; Messoud Ashina

doi:10.1111/j.1526-4610.2011.01861.x

Calcitonin gene-related peptide does not cause migraine attacks in patients with familial hemiplegic migraine

Jakob M Hansen, Lise L Thomsen, Jes Olesen, Messoud Ashina

49 Citationer (Scopus)

Abstract

Calcitonin gene-related peptide (CGRP) is a key molecule in migraine pathogenesis. Intravenous CGRP triggers migraine-like attacks in patients with migraine with aura and without aura. In contrast, patients with familial hemiplegic migraine (FHM) with known mutations did not report more migraine-like attacks compared to controls. Whether CGRP triggers migraine-like attacks in FHM patients without known mutations is unknown.

Originalsprog	Engelsk
Tidsskrift	Headache
Vol/bind	51
Udgave nummer	4
Sider (fra-til)	544-53
Antal sider	10
ISSN	0017-8748
DOI	https://doi.org/10.1111/j.1526-4610.2011.01861.x
Status	Udgivet - 2011

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10.1111/j.1526-4610.2011.01861.x

Citationsformater

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title = "Calcitonin gene-related peptide does not cause migraine attacks in patients with familial hemiplegic migraine",

abstract = "Calcitonin gene-related peptide (CGRP) is a key molecule in migraine pathogenesis. Intravenous CGRP triggers migraine-like attacks in patients with migraine with aura and without aura. In contrast, patients with familial hemiplegic migraine (FHM) with known mutations did not report more migraine-like attacks compared to controls. Whether CGRP triggers migraine-like attacks in FHM patients without known mutations is unknown.",

author = "Hansen, {Jakob M} and Thomsen, {Lise L} and Jes Olesen and Messoud Ashina",

note = "{\textcopyright} 2011 American Headache Society.",

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T1 - Calcitonin gene-related peptide does not cause migraine attacks in patients with familial hemiplegic migraine

AU - Hansen, Jakob M

AU - Thomsen, Lise L

AU - Olesen, Jes

AU - Ashina, Messoud

PY - 2011

Y1 - 2011

N2 - Calcitonin gene-related peptide (CGRP) is a key molecule in migraine pathogenesis. Intravenous CGRP triggers migraine-like attacks in patients with migraine with aura and without aura. In contrast, patients with familial hemiplegic migraine (FHM) with known mutations did not report more migraine-like attacks compared to controls. Whether CGRP triggers migraine-like attacks in FHM patients without known mutations is unknown.

AB - Calcitonin gene-related peptide (CGRP) is a key molecule in migraine pathogenesis. Intravenous CGRP triggers migraine-like attacks in patients with migraine with aura and without aura. In contrast, patients with familial hemiplegic migraine (FHM) with known mutations did not report more migraine-like attacks compared to controls. Whether CGRP triggers migraine-like attacks in FHM patients without known mutations is unknown.

U2 - 10.1111/j.1526-4610.2011.01861.x

DO - 10.1111/j.1526-4610.2011.01861.x

M3 - Journal article

C2 - 21457239

SN - 0017-8748

VL - 51

SP - 544

EP - 553

JO - Headache

JF - Headache

IS - 4

ER -

Calcitonin gene-related peptide does not cause migraine attacks in patients with familial hemiplegic migraine

Abstract

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