C-type natriuretic-derived peptides as biomarkers in human disease

Solvej Kølvraa Lippert, Jens Peter Goetze

14 Citationer (Scopus)


The natriuretic peptide system comprises three structurally related peptides: atrial natriuretic peptide, B-type natriuretic peptide and C-type natriuretic peptide. In circulation, they play an important endocrine role in the regulation of cardiovascular homeostasis by maintaining blood pressure and extracellular fluid volume. Atrial natriuretic peptide and B-type natriuretic peptide have gained considerable diagnostic interest as biomarkers in cardiovascular disease. By contrast, C-type natriuretic peptide has not yet been ascribed a role in human diagnostics. This perspective aims at recapitulating the present biochemical and clinical issues concerning C-type natriuretic peptide measurement in plasma as a potential biomarker.
TidsskriftBiomarkers in Medicine
Udgave nummer4
Sider (fra-til)631-9
Antal sider9
StatusUdgivet - 1 aug. 2010


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