@article{a38679795e3242c1a136c94e61d805ff,
title = "Bringing Radiotracing to Titanium-Based Antineoplastics: Solid Phase Radiosynthesis, PET and ex Vivo Evaluation of Antitumor Agent [(45)Ti](salan)Ti(dipic)",
abstract = "We present a novel solid-phase based (45)Ti radiolabeling methodology and the implementation of (45)Ti-PET in titanium-based antineoplastics using the showcase compound [(45)Ti](salan)Ti(dipic). This development is intended to allow elucidation of the biodistribution and pharmacokinetics of promising new Ti-based therapeutics.",
keywords = "Animals, Antineoplastic Agents, Coordination Complexes, HT29 Cells, Humans, Mice, Nude, Positron-Emission Tomography, Radiopharmaceuticals, Solid-Phase Synthesis Techniques, Tissue Distribution, Titanium, Xenograft Model Antitumor Assays",
author = "Gregory Severin and Nielsen, {Carsten H} and Jensen, {Andreas I} and Jesper Fonslet and Andreas Kj{\ae}r and Fedor Zhuravlev",
year = "2015",
month = sep,
day = "24",
doi = "10.1021/acs.jmedchem.5b01167",
language = "English",
volume = "58",
pages = "7591--5",
journal = "Journal of Medicinal Chemistry",
issn = "0022-2623",
publisher = "American Chemical Society",
number = "18",
}