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Region Hovedstaden - en del af Københavns Universitetshospital
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Brief Report: long-term outcome of a randomized clinical trial comparing methotrexate to cyclophosphamide for remission induction in early systemic antineutrophil cytoplasmic antibody-associated vasculitis

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The NORAM (Nonrenal Wegener's Granulomatosis Treated Alternatively with Methotrexate [MTX]) trial demonstrated that MTX can replace cyclophosphamide (CYC) as remission-inducing treatment for patients with newly diagnosed early systemic antineutrophil cytoplasmic antibody-associated vasculitis. Duration of relapse-free survival was longer among CYC-treated patients than among MTX-treated patients during short-term followup. The aim of the present study was to describe the long-term outcome in patients enrolled in the randomized clinical trial.
OriginalsprogEngelsk
TidsskriftArthritis & Rheumatism
Vol/bind64
Udgave nummer10
Sider (fra-til)3472-7
Antal sider6
ISSN0004-3591
DOI
StatusUdgivet - 2012

ID: 36820827