Bone mass development in childhood and its association with physical activity and vitamin D levels. The CHAMPS-Study DK

Maria Sode Rønne, Malene Heidemann, Louise Lylloff, Anders J Schou, Jakob Tarp, Jens Ole Laursen, Niklas Rye Jørgensen, Steffen Husby, Niels Wedderkopp, Christian Mølgaard

10 Citationer (Scopus)

Abstract

This longitudinal study examined associations of bone mass with physical activity and vitamin D level over more than 6 years through puberty. A total of 663 participants (320 boys) with mean age 9.6 years at baseline (10-17 years at follow-up), underwent dual energy X-ray absorptiometry, anthropometry and blood samples for vitamin D at least twice during the study period (with three possible time-points). Physical activity was assessed using accelerometers at follow-up. A positive association was found between percent time spent at vigorous physical activity and total-body less head bone mineral content (β = 5.8, p = 0.002). The magnitude of this association increased with maturational development; thus physical activity may have a greater influence on bone mass in the more mature participants. The vitamin D levels were also positively associated with bone mass. A high degree of tracking was observed with changes in anthropometric Z scores predictive of deviation from tracking. No environmental factor predicted deviation from tracking.

OriginalsprogEngelsk
TidsskriftCalcified Tissue International
Vol/bind104
Udgave nummer1
Sider (fra-til)1-13
Antal sider13
ISSN0171-967X
DOI
StatusUdgivet - 15 jan. 2019

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