@article{6e20ecc72f204dfe88e691c624128212,
title = "Body mass index and poststroke mortality",
abstract = "BACKGROUND: Obesity is an established cardiovascular risk factor. We studied the association between body mass index (BMI) and all-cause mortality after stroke. METHODS: A registry started in 2001 with the aim to register all hospitalized stroke patients in Denmark now includes 21,884 patients in whom BMI was recorded. There are five BMI groups: underweight (BMI < 18.5), normal weight (BMI 18.5-24.9), overweight (BMI 25.0-29.9), obese (BMI 30.0-34.9) and severely obese (BMI > or = 35). All patients underwent an evaluation including stroke severity, computed tomography, and cardiovascular risk factors. Survival was followed up to 5 years after stroke (median 1.5 years). Independent predictors of death were identified by means of a survival model based on 13,242 individuals with a complete data set. RESULTS: Compared to normal-weight patients, mortality was lower in overweight [hazard rate (HR) 0.73, 95\% CI 0.66-0.81], obese (HR 0.84, 95\% CI 0.73-0.98) and severely obese stroke patients (HR 0.84, 95\% CI 0.64-1.10), while mortality was higher in underweight patients (HR 1.63, 95\% CI 1.41-1.90). CONCLUSIONS: Poststroke mortality is inversely related to BMI: overweight and obese stroke patients have a lower poststroke mortality rate than normal-weight and underweight patients.",
keywords = "Adult, Aged, Body Mass Index, Cohort Studies, Comorbidity, Denmark, Female, Follow-Up Studies, Humans, Male, Middle Aged, Obesity, Risk Factors, Stroke, Survival Analysis",
author = "Olsen, \{Tom Skyh{\o}j\} and Christian Dehlendorff and Petersen, \{Hans Gregers\} and Andersen, \{Klaus Kaae\}",
note = "2008 S. Karger AG, Basel",
year = "2008",
doi = "10.1159/000118945",
language = "English",
volume = "30",
pages = "93--100",
journal = "Neuroepidemiology",
issn = "0251-5350",
publisher = "S. Karger AG",
number = "2",
}