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Blood-brain barrier permeability of normal appearing white matter in relapsing-remitting multiple sclerosis

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Multiple sclerosis (MS) affects the integrity of the blood-brain barrier (BBB). Contrast-enhanced T1 weighted magnetic resonance imaging (MRI) is widely used to characterize location and extent of BBB disruptions in focal MS lesions. We employed quantitative T1 measurements before and after the intravenous injection of a paramagnetic contrast agent to assess BBB permeability in the normal appearing white matter (NAWM) in patients with relapsing-remitting MS (RR-MS).
OriginalsprogEngelsk
TidsskriftP L o S One
Vol/bind8
Tidsskriftsnummer2
Sider (fra-til)e56375
ISSN1932-6203
DOI
StatusUdgivet - 2013

ID: 41127010