Blood profiling of proteins and steroids during weight maintenance with manipulation of dietary protein level and glycaemic index

Ping Wang; Claus Holst; Arne Astrup; Freek G Bouwman; Sanne van Otterdijk; Will K W H Wodzig; Malene R Andersen; Marleen A van Baak; Lone Graasbøl Rasmussen; J Alfredo Martinez; Susan A Jebb; Andreas F H Pfeiffer; Anthony Kafatos; Teodora Handjieva-Darlenska; Petr Hlavaty; Wim H M Saris; Edwin C M Mariman

doi:10.1017/S0007114511002583

Blood profiling of proteins and steroids during weight maintenance with manipulation of dietary protein level and glycaemic index

Ping Wang, Claus Holst, Arne Astrup, Freek G Bouwman, Sanne van Otterdijk, Will K W H Wodzig, Malene R Andersen, Marleen A van Baak, Lone Graasbøl Rasmussen, J Alfredo Martinez, Susan A Jebb, Andreas F H Pfeiffer, Anthony Kafatos, Teodora Handjieva-Darlenska, Petr Hlavaty, Wim H M Saris, Edwin C M Mariman

20 Citationer (Scopus)

Abstract

Weight regain after weight loss is common. In the Diogenes dietary intervention study, a high-protein and low-glycaemic index (GI) diet improved weight maintenance. The objective of the present study was to identify (1) blood profiles associated with continued weight loss and weight regain (2) blood biomarkers of dietary protein and GI levels during the weight-maintenance phase. Blood samples were collected at baseline, after 8 weeks of low-energy diet-induced weight loss and after a 6-month dietary intervention period from female continued weight losers (n 48) and weight regainers (n 48), evenly selected from four dietary groups that varied in protein and GI levels. The blood concentrations of twenty-nine proteins and three steroid hormones were measured. The changes in analytes during weight maintenance largely correlated negatively with the changes during weight loss, with some differences between continued weight losers and weight regainers. Increases in leptin (LEP) and C-reactive protein (CRP) were significantly associated with weight regain (P

Originalsprog	Engelsk
Tidsskrift	British Journal of Nutrition
Sider (fra-til)	1-14
Antal sider	14
ISSN	0007-1145
DOI	https://doi.org/10.1017/S0007114511002583
Status	Udgivet - 23 jun. 2011

Adgang til dokumentet

10.1017/S0007114511002583

Citationsformater

Wang, P., Holst, C., Astrup, A., Bouwman, F. G., van Otterdijk, S., Wodzig, W. K. W. H., Andersen, M. R., van Baak, M. A., Rasmussen, L. G., Alfredo Martinez, J., Jebb, S. A., Pfeiffer, A. F. H., Kafatos, A., Handjieva-Darlenska, T., Hlavaty, P., Saris, W. H. M., & Mariman, E. C. M. (2011). Blood profiling of proteins and steroids during weight maintenance with manipulation of dietary protein level and glycaemic index. British Journal of Nutrition, 1-14. https://doi.org/10.1017/S0007114511002583

Wang, P, Holst, C, Astrup, A, Bouwman, FG, van Otterdijk, S, Wodzig, WKWH, Andersen, MR, van Baak, MA, Rasmussen, LG, Alfredo Martinez, J, Jebb, SA, Pfeiffer, AFH, Kafatos, A, Handjieva-Darlenska, T, Hlavaty, P, Saris, WHM & Mariman, ECM 2011, 'Blood profiling of proteins and steroids during weight maintenance with manipulation of dietary protein level and glycaemic index', British Journal of Nutrition, s. 1-14. https://doi.org/10.1017/S0007114511002583

@article{55081aea88794972a0f3fd548f93ee09,

title = "Blood profiling of proteins and steroids during weight maintenance with manipulation of dietary protein level and glycaemic index",

abstract = "Weight regain after weight loss is common. In the Diogenes dietary intervention study, a high-protein and low-glycaemic index (GI) diet improved weight maintenance. The objective of the present study was to identify (1) blood profiles associated with continued weight loss and weight regain (2) blood biomarkers of dietary protein and GI levels during the weight-maintenance phase. Blood samples were collected at baseline, after 8 weeks of low-energy diet-induced weight loss and after a 6-month dietary intervention period from female continued weight losers (n 48) and weight regainers (n 48), evenly selected from four dietary groups that varied in protein and GI levels. The blood concentrations of twenty-nine proteins and three steroid hormones were measured. The changes in analytes during weight maintenance largely correlated negatively with the changes during weight loss, with some differences between continued weight losers and weight regainers. Increases in leptin (LEP) and C-reactive protein (CRP) were significantly associated with weight regain (P ",

author = "Ping Wang and Claus Holst and Arne Astrup and Bouwman, {Freek G} and {van Otterdijk}, Sanne and Wodzig, {Will K W H} and Andersen, {Malene R} and {van Baak}, {Marleen A} and Rasmussen, {Lone Graasb{\o}l} and {Alfredo Martinez}, J and Jebb, {Susan A} and Pfeiffer, {Andreas F H} and Anthony Kafatos and Teodora Handjieva-Darlenska and Petr Hlavaty and Saris, {Wim H M} and Mariman, {Edwin C M}",

year = "2011",

month = jun,

day = "23",

doi = "10.1017/S0007114511002583",

language = "English",

pages = "1--14",

journal = "British Journal of Nutrition",

issn = "0007-1145",

publisher = "Cambridge University Press",

}

TY - JOUR

T1 - Blood profiling of proteins and steroids during weight maintenance with manipulation of dietary protein level and glycaemic index

AU - Wang, Ping

AU - Holst, Claus

AU - Astrup, Arne

AU - Bouwman, Freek G

AU - van Otterdijk, Sanne

AU - Wodzig, Will K W H

AU - Andersen, Malene R

AU - van Baak, Marleen A

AU - Rasmussen, Lone Graasbøl

AU - Alfredo Martinez, J

AU - Jebb, Susan A

AU - Pfeiffer, Andreas F H

AU - Kafatos, Anthony

AU - Handjieva-Darlenska, Teodora

AU - Hlavaty, Petr

AU - Saris, Wim H M

AU - Mariman, Edwin C M

PY - 2011/6/23

Y1 - 2011/6/23

N2 - Weight regain after weight loss is common. In the Diogenes dietary intervention study, a high-protein and low-glycaemic index (GI) diet improved weight maintenance. The objective of the present study was to identify (1) blood profiles associated with continued weight loss and weight regain (2) blood biomarkers of dietary protein and GI levels during the weight-maintenance phase. Blood samples were collected at baseline, after 8 weeks of low-energy diet-induced weight loss and after a 6-month dietary intervention period from female continued weight losers (n 48) and weight regainers (n 48), evenly selected from four dietary groups that varied in protein and GI levels. The blood concentrations of twenty-nine proteins and three steroid hormones were measured. The changes in analytes during weight maintenance largely correlated negatively with the changes during weight loss, with some differences between continued weight losers and weight regainers. Increases in leptin (LEP) and C-reactive protein (CRP) were significantly associated with weight regain (P

AB - Weight regain after weight loss is common. In the Diogenes dietary intervention study, a high-protein and low-glycaemic index (GI) diet improved weight maintenance. The objective of the present study was to identify (1) blood profiles associated with continued weight loss and weight regain (2) blood biomarkers of dietary protein and GI levels during the weight-maintenance phase. Blood samples were collected at baseline, after 8 weeks of low-energy diet-induced weight loss and after a 6-month dietary intervention period from female continued weight losers (n 48) and weight regainers (n 48), evenly selected from four dietary groups that varied in protein and GI levels. The blood concentrations of twenty-nine proteins and three steroid hormones were measured. The changes in analytes during weight maintenance largely correlated negatively with the changes during weight loss, with some differences between continued weight losers and weight regainers. Increases in leptin (LEP) and C-reactive protein (CRP) were significantly associated with weight regain (P

U2 - 10.1017/S0007114511002583

DO - 10.1017/S0007114511002583

M3 - Journal article

C2 - 21733334

SN - 0007-1145

SP - 1

EP - 14

JO - British Journal of Nutrition

JF - British Journal of Nutrition

ER -

Blood profiling of proteins and steroids during weight maintenance with manipulation of dietary protein level and glycaemic index

Abstract

Adgang til dokumentet

Fingeraftryk

Citationsformater