Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Bipolar disorders

Publikation: Bidrag til tidsskriftReviewForskningpeer review

DOI

  1. Gestational diabetes mellitus

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  2. Testicular cancer

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  3. Invasive candidiasis

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  4. Antiphospholipid syndrome

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  5. Narcolepsy

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  1. Functional hypoxia drives neuroplasticity and neurogenesis via brain erythropoietin

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. S100B and brain derived neurotrophic factor in monozygotic twins with, at risk of and without affective disorders

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Erythropoietin as candidate for supportive treatment of severe COVID-19

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  • Eduard Vieta
  • Michael Berk
  • Thomas G Schulze
  • André F Carvalho
  • Trisha Suppes
  • Joseph R Calabrese
  • Keming Gao
  • Kamilla W Miskowiak
  • Iria Grande
Vis graf over relationer

Bipolar disorders are chronic and recurrent disorders that affect >1% of the global population. Bipolar disorders are leading causes of disability in young people as they can lead to cognitive and functional impairment and increased mortality, particularly from suicide and cardiovascular disease. Psychiatric and nonpsychiatric medical comorbidities are common in patients and might also contribute to increased mortality. Bipolar disorders are some of the most heritable psychiatric disorders, although a model with gene-environment interactions is believed to best explain the aetiology. Early and accurate diagnosis is difficult in clinical practice as the onset of bipolar disorder is commonly characterized by nonspecific symptoms, mood lability or a depressive episode, which can be similar in presentation to unipolar depression. Moreover, patients and their families do not always understand the significance of their symptoms, especially with hypomanic or manic symptoms. As specific biomarkers for bipolar disorders are not yet available, careful clinical assessment remains the cornerstone of diagnosis. The detection of hypomanic symptoms and longtudinal clinical assessment are crucial to differentiate a bipolar disorder from other conditions. Optimal early treatment of patients with evidence-based medication (typically mood stabilizers and antipsychotics) and psychosocial strategies is necessary.

OriginalsprogEngelsk
TidsskriftNature reviews. Disease primers
Vol/bind4
Sider (fra-til)18008
ISSN2056-676X
DOI
StatusUdgivet - 8 mar. 2018

ID: 53743952