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Bipolar disorders

Publikation: Bidrag til tidsskriftReviewForskningpeer review

DOI

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  1. Characteristics influencing expected cognitive performance during hypoglycaemia in type 2 diabetes

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Assessment and treatment of cognitive impairments in patients with affective disorders

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Effects of mild hypoglycaemia on cognitive function in type 2 diabetes: a randomised crossover trial

    Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

  • Eduard Vieta
  • Michael Berk
  • Thomas G Schulze
  • André F Carvalho
  • Trisha Suppes
  • Joseph R Calabrese
  • Keming Gao
  • Kamilla W Miskowiak
  • Iria Grande
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Bipolar disorders are chronic and recurrent disorders that affect >1% of the global population. Bipolar disorders are leading causes of disability in young people as they can lead to cognitive and functional impairment and increased mortality, particularly from suicide and cardiovascular disease. Psychiatric and nonpsychiatric medical comorbidities are common in patients and might also contribute to increased mortality. Bipolar disorders are some of the most heritable psychiatric disorders, although a model with gene-environment interactions is believed to best explain the aetiology. Early and accurate diagnosis is difficult in clinical practice as the onset of bipolar disorder is commonly characterized by nonspecific symptoms, mood lability or a depressive episode, which can be similar in presentation to unipolar depression. Moreover, patients and their families do not always understand the significance of their symptoms, especially with hypomanic or manic symptoms. As specific biomarkers for bipolar disorders are not yet available, careful clinical assessment remains the cornerstone of diagnosis. The detection of hypomanic symptoms and longtudinal clinical assessment are crucial to differentiate a bipolar disorder from other conditions. Optimal early treatment of patients with evidence-based medication (typically mood stabilizers and antipsychotics) and psychosocial strategies is necessary.

OriginalsprogEngelsk
TidsskriftNature reviews. Disease primers
Vol/bind4
Sider (fra-til)18008
ISSN2056-676X
DOI
StatusUdgivet - 8 mar. 2018

ID: 53743952