Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Biomechanical properties of the patellar tendon in children with heritable connective tissue disorders

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. High bone mineral density in lifelong trained female team handball players and young elite football players

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. The physiology of rowing with perspective on training and health

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  3. Ultrasound speckle tracking of Achilles tendon in individuals with unilateral tendinopathy: a pilot study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Investigating circadian clock gene expression in human tendon biopsies from acute exercise and immobilization studies

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Collagen Growth Pattern in Human Articular Cartilage of the Knee

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Mechanical properties of human patellar tendon collagen fibrils. An exploratory study of aging and sex

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Psychiatric disorders in individuals with neurofibromatosis 1 in Denmark: A nationwide register-based cohort study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

PURPOSE: Hereditary connective tissue disorders (HCTDs), such as classic Ehlers-Danlos syndrome (cEDS) and Marfan syndrome (MS) share overlapping features like hypermobility and tissue fragility. In clinical practice it remains a challenge to distinguish children and adolescents with HCTD from healthy children. The purpose of this study was to investigate the biomechanical properties of the patellar tendon and joint laxity (Beighton score) in children with HCTDs (n = 7) compared to healthy controls (n = 14).

METHODS: The mechanical properties of the patellar tendon were assessed using simultaneous force and ultrasonographic measurements during isometric ramp contractions. Ultrasonography was also used to measure tendon dimensions. The HCTD children were matched with 2 healthy controls with regard to age, body mass index (BMI), sex and physical activity level.

RESULTS: The HCTD children had a greater degree of joint laxity (P < 0.01). Although, the patellar tendon dimensions did not differ significantly between the two groups, the HCTD children showed a tendency toward a larger patellar tendon cross-sectional area (CSA) (35%, P = 0.19). Moreover, stiffness did not differ between the two groups, but secant modulus was 27% lower in children with a HCTD (P = 0.05) at common force and 34% lower at maximum force (P = 0.02).

CONCLUSIONS: The present study demonstrates for the first time that children with HCTDs have lower material properties (modulus) of their patellar tendon, which may be indicative of general impairment of connective tissue mechanics related to their increased joint laxity.

OriginalsprogEngelsk
TidsskriftEuropean Journal of Applied Physiology
Vol/bind118
Udgave nummer7
Sider (fra-til)1301-1307
Antal sider7
ISSN1439-6319
DOI
StatusUdgivet - jul. 2018

ID: 54942861