Biological variations in plasma VEGF and VEGFR-1 may compromise their biomarker value in colorectal cancer

Mads Nordahl Svendsen; Nils Brünner; Ib J Christensen; Henriette Ytting; Camilla Bentsen; Anne Fog Lomholt; Hans J Nielsen

doi:10.3109/00365513.2010.521254

Biological variations in plasma VEGF and VEGFR-1 may compromise their biomarker value in colorectal cancer

Mads Nordahl Svendsen, Nils Brünner, Ib J Christensen, Henriette Ytting, Camilla Bentsen, Anne Fog Lomholt, Hans J Nielsen

6 Citationer (Scopus)

Abstract

Vascular Endothelial Growth Factor (VEGF) plays a prominent role in tumor angiogenesis and plasma VEGF concentration may carry prognostic information in colorectal cancer. The VEGF receptor 1 (VEGFR-1) is a regulatory receptor which is shredded into plasma of patients with colorectal cancer. For both molecules, large biological variation and lack of standardization of assay procedures are major challenges.

Originalsprog	Engelsk
Tidsskrift	Scandinavian Journal of Clinical & Laboratory Investigation
Vol/bind	70
Udgave nummer	7
Sider (fra-til)	503-11
Antal sider	9
ISSN	0036-5513
DOI	https://doi.org/10.3109/00365513.2010.521254
Status	Udgivet - 1 nov. 2010

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10.3109/00365513.2010.521254

Citationsformater

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title = "Biological variations in plasma VEGF and VEGFR-1 may compromise their biomarker value in colorectal cancer",

abstract = "Vascular Endothelial Growth Factor (VEGF) plays a prominent role in tumor angiogenesis and plasma VEGF concentration may carry prognostic information in colorectal cancer. The VEGF receptor 1 (VEGFR-1) is a regulatory receptor which is shredded into plasma of patients with colorectal cancer. For both molecules, large biological variation and lack of standardization of assay procedures are major challenges.",

author = "{Nordahl Svendsen}, Mads and Nils Br{\"u}nner and Christensen, {Ib J} and Henriette Ytting and Camilla Bentsen and Lomholt, {Anne Fog} and Nielsen, {Hans J}",

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T1 - Biological variations in plasma VEGF and VEGFR-1 may compromise their biomarker value in colorectal cancer

AU - Nordahl Svendsen, Mads

AU - Brünner, Nils

AU - Christensen, Ib J

AU - Ytting, Henriette

AU - Bentsen, Camilla

AU - Lomholt, Anne Fog

AU - Nielsen, Hans J

PY - 2010/11/1

Y1 - 2010/11/1

N2 - Vascular Endothelial Growth Factor (VEGF) plays a prominent role in tumor angiogenesis and plasma VEGF concentration may carry prognostic information in colorectal cancer. The VEGF receptor 1 (VEGFR-1) is a regulatory receptor which is shredded into plasma of patients with colorectal cancer. For both molecules, large biological variation and lack of standardization of assay procedures are major challenges.

AB - Vascular Endothelial Growth Factor (VEGF) plays a prominent role in tumor angiogenesis and plasma VEGF concentration may carry prognostic information in colorectal cancer. The VEGF receptor 1 (VEGFR-1) is a regulatory receptor which is shredded into plasma of patients with colorectal cancer. For both molecules, large biological variation and lack of standardization of assay procedures are major challenges.

U2 - 10.3109/00365513.2010.521254

DO - 10.3109/00365513.2010.521254

M3 - Journal article

C2 - 20873967

SN - 0036-5513

VL - 70

SP - 503

EP - 511

JO - Scandinavian Journal of Clinical & Laboratory Investigation

JF - Scandinavian Journal of Clinical & Laboratory Investigation

IS - 7

ER -

Biological variations in plasma VEGF and VEGFR-1 may compromise their biomarker value in colorectal cancer

Abstract

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