Biofilms can act as plasmid reserves in the absence of plasmid specific selection

Henriette Lyng Røder, Urvish Trivedi, Jakob Russel, Kasper Nørskov Kragh, Jakob Herschend, Ida Thalsø-Madsen, Tim Tolker-Nielsen, Thomas Bjarnsholt, Mette Burmølle, Jonas Stenløkke Madsen

18 Citationer (Scopus)

Abstract

Plasmids facilitate rapid bacterial adaptation by shuttling a wide variety of beneficial traits across microbial communities. However, under non-selective conditions, maintaining a plasmid can be costly to the host cell. Nonetheless, plasmids are ubiquitous in nature where bacteria adopt their dominant mode of life - biofilms. Here, we demonstrate that biofilms can act as spatiotemporal reserves for plasmids, allowing them to persist even under non-selective conditions. However, under these conditions, spatial stratification of plasmid-carrying cells may promote the dispersal of cells without plasmids, and biofilms may thus act as plasmid sinks.

OriginalsprogEngelsk
Artikelnummer78
TidsskriftNPJ biofilms and microbiomes
Vol/bind7
Udgave nummer1
Sider (fra-til)78
Antal sider6
ISSN2055-5008
DOI
StatusUdgivet - 7 okt. 2021

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