Biochemical activity induced by a germline variation in KLK3 (PSA) associates with cellular function and clinical outcome in prostate cancer

Keyphrases

• Clinical Outcomes 100%
• Functional Outcome 100%
• Prostate Cancer 100%
• Prostate Cancer Risk 100%
• Cell Behavior 100%
• Germline Variation 100%
• Biochemical Activity 100%
• SNP 50%
• Total PSA 50%
• Delayed Diagnosis 25%
• Genetic Variation 25%
• Metastasis 25%
• Subcutaneous Tumor 25%
• Proteolytic Activity 25%
• Aggressive Disease 25%
• In Vivo Model 25%
• Tumor Burden 25%
• Functional Relevance 25%
• SNP Variants 25%
• Metastatic Potential 25%
• SNP Alleles 25%
• Biochemical Characterization 25%
• Osteolytic 25%
• Experimental Metastasis 25%
• Cancer Pathogenesis 25%
• SNP Association 25%
• Nonsynonymous 25%
• Reduced Serum 25%

Biochemistry, Genetics and Molecular Biology

• Cell Function 100%
• Single Nucleotide Polymorphism 100%
• Germline 100%
• Germ Cell 100%
• Allele 20%
• Genetic Variation 20%
• Genetic Divergence 20%
• Osteolysis 20%
• Tumor Volume 20%
• Protein Catabolism 20%