Bicyclo[3.2.0]heptane as a Core Structure for Conformational Locking of 1,3-Bis-Pharmacophores, Exemplified by GABA

Keyphrases

• Core Structure 100%
• Heptane 100%
• Pharmacophore 100%
• Bicyclol 100%
• Conformational Locking 100%
• N-Boc 60%
• Stereoisomers 40%
• Aminobutyric Acid 20%
• Intrinsic Properties 20%
• Carboxylic Acids 20%
• X-ray Crystal Structure 20%
• Amino Group 20%
• In Silico Modeling 20%
• Axial Position 20%
• Structural Concepts 20%
• Disubstituted 20%
• Urethane 20%
• Crystal Packing 20%
• Pharmacophoric Group 20%
• Substitution Pattern 20%

Biochemistry, Genetics and Molecular Biology

• Conformation 100%
• Stereoisomerism 100%
• Pharmacophore 100%
• Computer Model 50%
• X Ray 50%
• Crystal Structure 50%

Medicine and Dentistry

• Gamma-Aminobutyric Acid 100%
• Pharmacophore 100%
• In Silico 33%
• Carboxylic Acid 33%
• Urethan 33%