Abstract
ABSTRACT: Among critically ill patients, the diagnosis of bloodstream infection poses a major challenge. Current standard bacterial identification based on blood culture platforms is intrinsically time-consuming and slow. The continuous evolvement of molecular techniques has the potential of providing a faster, more sensitive and direct identification of causative pathogens without prior need for cultivation. This may ultimately impact clinical decision-making and antimicrobial treatment. This review summarises the currently available technologies, their strengths and limitations and the obstacles that have to be overcome in order to develop a satisfactory bedside point-of-care diagnostic tool for detection of bloodstream infection.
Originalsprog | Engelsk |
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Tidsskrift | Critical Care (Online Edition) |
Vol/bind | 16 |
Udgave nummer | 3 |
Sider (fra-til) | 222 |
ISSN | 1466-609X |
DOI | |
Status | Udgivet - 2012 |