Behandling af metforminassocieret laktatacidose med hæmodialyse

Karin Schousboe; Daniel El Fassi; Erik Lilja Secher; Hanne Elming; Knud Rasmussen; Mads Hornum

Behandling af metforminassocieret laktatacidose med hæmodialyse

Karin Schousboe, Daniel El Fassi, Erik Lilja Secher, Hanne Elming, Knud Rasmussen, Mads Hornum

4 Citationer (Scopus)

Abstract

Metformin-associated lactate acidosis is rare but serious and characterized by metabolic acidosis and elevated lactate. We describe a single-institution experience of four cases in one year. Despite pH levels of 6.85 to 7.12 and lactate levels of 11-28 mmol/l three of the patients survived. Two of the patients had normal kidney function previous to hospitalization. Treatment includes fluid replacement, IV sodium bicarbonate and haemodialysis.

Bidragets oversatte titel	Treatment of metformin-associated lactate acidosis by haemodialysis
Originalsprog	Dansk
Tidsskrift	Ugeskrift for Laeger
Vol/bind	174
Udgave nummer	23
Sider (fra-til)	1604-6
Antal sider	3
ISSN	0041-5782
Status	Udgivet - 2012

Emneord

Acidosis, Lactic
Aged
Diabetes Mellitus, Type 2
Female
Humans
Hypoglycemic Agents
Male
Metformin
Renal Dialysis

Citationsformater

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abstract = "Metformin-associated lactate acidosis is rare but serious and characterized by metabolic acidosis and elevated lactate. We describe a single-institution experience of four cases in one year. Despite pH levels of 6.85 to 7.12 and lactate levels of 11-28 mmol/l three of the patients survived. Two of the patients had normal kidney function previous to hospitalization. Treatment includes fluid replacement, IV sodium bicarbonate and haemodialysis.",

keywords = "Acidosis, Lactic, Aged, Diabetes Mellitus, Type 2, Female, Humans, Hypoglycemic Agents, Male, Metformin, Renal Dialysis",

author = "Karin Schousboe and {El Fassi}, Daniel and Secher, {Erik Lilja} and Hanne Elming and Knud Rasmussen and Mads Hornum",

year = "2012",

language = "Dansk",

volume = "174",

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journal = "Ugeskrift for Laeger",

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TY - JOUR

T1 - Behandling af metforminassocieret laktatacidose med hæmodialyse

AU - Schousboe, Karin

AU - El Fassi, Daniel

AU - Secher, Erik Lilja

AU - Elming, Hanne

AU - Rasmussen, Knud

AU - Hornum, Mads

PY - 2012

Y1 - 2012

N2 - Metformin-associated lactate acidosis is rare but serious and characterized by metabolic acidosis and elevated lactate. We describe a single-institution experience of four cases in one year. Despite pH levels of 6.85 to 7.12 and lactate levels of 11-28 mmol/l three of the patients survived. Two of the patients had normal kidney function previous to hospitalization. Treatment includes fluid replacement, IV sodium bicarbonate and haemodialysis.

AB - Metformin-associated lactate acidosis is rare but serious and characterized by metabolic acidosis and elevated lactate. We describe a single-institution experience of four cases in one year. Despite pH levels of 6.85 to 7.12 and lactate levels of 11-28 mmol/l three of the patients survived. Two of the patients had normal kidney function previous to hospitalization. Treatment includes fluid replacement, IV sodium bicarbonate and haemodialysis.

KW - Acidosis, Lactic

KW - Aged

KW - Diabetes Mellitus, Type 2

KW - Female

KW - Humans

KW - Hypoglycemic Agents

KW - Male

KW - Metformin

KW - Renal Dialysis

M3 - Tidsskriftartikel

C2 - 22673381

SN - 0041-5782

VL - 174

SP - 1604

EP - 1606

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 23

ER -

Behandling af metforminassocieret laktatacidose med hæmodialyse

Abstract

Emneord

Fingeraftryk

Citationsformater