Behandling af heparininduceret immunbetinget trombocytopeni med argatroban

Abstract

Heparin-induced immune-mediated thrombocytopenia (HIT) is a life-threatening complication of heparin treatment. When HIT is clinically suspected, heparin treatment should immediately be replaced with an alternative, fast-acting, anticoagulant agent, and blood tests should be carried out to verify or to exclude the diagnosis. Argatroban has recently been approved for HIT treatment in Denmark. Recommendations for dosing of argatroban in HIT patients with and without comorbities are presented.

Bidragets oversatte titelArgatroban treatment of heparin-induced immune-mediated thrombocytopenia
OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind171
Udgave nummer8
Sider (fra-til)610-1
Antal sider2
ISSN0041-5782
StatusUdgivet - 16 feb. 2009

Emneord

  • Anticoagulants/adverse effects
  • Arginine/analogs & derivatives
  • Fibrinolytic Agents/adverse effects
  • Heparin/adverse effects
  • Humans
  • Pipecolic Acids/administration & dosage
  • Platelet Aggregation Inhibitors/administration & dosage
  • Sulfonamides
  • Thrombocytopenia/chemically induced

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