Baseline characteristics in the Aliskiren Trial in Type 2 Diabetes Using Cardio-Renal Endpoints (ALTITUDE)

Hans-Henrik Parving, Barry M Brenner, John J V McMurray, Dick de Zeeuw, Steven M Haffner, Scott D Solomon, Nish Chaturvedi, Frederik Persson, Maria Nicolaides, Alexia Richard, Zhihua Xiang, Juergen Armbrecht, Marc A Pfeffer, ALTITUDE Investigators

    61 Citationer (Scopus)

    Abstract

    Patients with type 2 diabetes are at enhanced risk for macro- and microvascular complications. Albuminuria and/or reduced kidney function further enhances the vascular risk. We initiated the Aliskiren Trial in Type 2 Diabetes Using Cardio-Renal Endpoints (ALTITUDE). Aliskiren, a novel direct renin inhibitor, which lowers plasma renin activity, may thereby provide greater cardio-renal protection compared with angiotensin converting enzyme inhibitor (ACEi) or angiotensin receptor blocker (ARB) alone.
    OriginalsprogEngelsk
    TidsskriftJournal of the Renin-Angiotensin-Aldosterone System
    Vol/bind13
    Udgave nummer3
    Sider (fra-til)387-93
    Antal sider7
    ISSN1470-3203
    DOI
    StatusUdgivet - 2012

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