Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Autoimmune diseases and infections as risk factors for schizophrenia

Publikation: Bidrag til tidsskriftReviewForskning

  1. Type 1 narcolepsy: a CD8(+) T cell-mediated disease?

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Effects of antiresorptive agents on osteomyelitis: novel insights into the pathogenesis of osteonecrosis of the jaw

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Hormonal contraception in obesity, the metabolic syndrome, and diabetes

    Publikation: Bidrag til tidsskriftKonferenceartikelForskningpeer review

  4. GABA regulates the rat hypothalamic-pituitary-adrenocortical axis via different GABA-A receptor alpha-subtypes

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Association between Mental Disorders and Subsequent Medical Conditions

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Association Between Neurological Disorders and Death by Suicide in Denmark

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

Immunological hypotheses have become increasingly prominent when studying the etiology of schizophrenia. Autoimmune diseases, and especially the number of infections requiring hospitalization, have been identified as significant risk factors for schizophrenia in a dose-response relationship, which seem compatible with an immunological hypothesis for subgroups of patients with schizophrenia. Inflammation and infections may affect the brain through many different pathways that are not necessarily mutually exclusive and can possibly increase the risk of schizophrenia in vulnerable individuals. However, the findings could also be an epiphenomenon and not causal, due to, for instance, common genetic vulnerability, which could be supported by the observations of an increased prevalence of autoimmune diseases and infections in parents of patients with schizophrenia. Nevertheless, autoimmune diseases and infections should be considered in the treatment of individuals with schizophrenia symptoms, and further research is needed of the immune system's possible contributing pathogenic factors in the etiology of schizophrenia.

OriginalsprogEngelsk
TidsskriftAnnals of the New York Academy of Sciences
Vol/bind1262
Sider (fra-til)56-66
Antal sider11
ISSN0077-8923
DOI
StatusUdgivet - jul. 2012

ID: 52667395