Autocorrelation and cross-correlation between hCGβ and PAPP-A in repeated sampling during first trimester of pregnancy

Pernille Nørgaard, Dave Wright, Susan Ball, Paul Newell, Ida Sejersdahl Kirkegaard, Olav Bjørn Petersen, Niels Uldbjerg, Niels Tørring, Finn Stener Jørgensen, Lennart Friis-Hansen, Charlotte Ekelund, Ann Tabor, Steen Sørensen

2 Citationer (Scopus)

Abstract

Theoretically, repeated sampling of free β-human chorionic gonadotropin (hCGβ) and pregnancy associated plasma protein-A (PAPP-A) in the first trimester of pregnancy might improve performance of risk assessment of trisomy 21 (T21). To assess the performance of a screening test involving repeated measures of biochemical markers, correlations between markers must be estimated. The aims of this study were to calculate the autocorrelation and cross-correlation between hCGβ and PAPP-A in the first trimester of pregnancy and to investigate the possible impact of gestational age at the first sample and time between sampling on the correlation.
OriginalsprogEngelsk
TidsskriftClinical Chemistry and Laboratory Medicine
Vol/bind51
Udgave nummer9
Sider (fra-til)1781-8
Antal sider8
ISSN1434-6621
DOI
StatusUdgivet - sep. 2013

Fingeraftryk

Dyk ned i forskningsemnerne om 'Autocorrelation and cross-correlation between hCGβ and PAPP-A in repeated sampling during first trimester of pregnancy'. Sammen danner de et unikt fingeraftryk.

Citationsformater