ATM mutations are associated with inactivation of the ARF-TP53 tumor suppressor pathway in diffuse large B-cell lymphoma

Keyphrases

• Tumor Protein p53 (TP53) 100%
• Diffuse Large B-cell Lymphoma (DLBCL) 100%
• Tumor Suppressor Activity 100%
• ATM mutation 100%
• Malignancy 20%
• Coding Sequence 20%
• In Cancer 20%
• B-cell Lymphoma 20%
• Lymphoma 20%
• Cellular Response 20%
• Novel mutation 20%
• DNA Damage 20%
• Germline mutation 20%
• Missense Variants 20%
• TP53 mutation 20%
• Mantle Cell Lymphoma 20%
• Acute Leukemia 20%
• B-cell Lymphoma 2 (Bcl-2) 20%
• Nonsense mutation 20%
• Genomic DNA (gDNA) 20%
• Serine-threonine Kinase 20%
• Follicular Lymphoma 20%
• Adult Acute Lymphoblastic Leukemia 20%
• Ink4a 20%
• Peripheral T-cell Lymphoma 20%
• Multisystem Disease 20%
• RNA Splicing 20%
• Biallelic mutations 20%
• Lymphoma Cells 20%
• Mutational Spectrum 20%
• ATM Gene 20%
• Ataxia Telangiectasia 20%
• Normal Variants 20%
• Lymphoid Neoplasms 20%
• T-cell Prolymphocytic Leukemia 20%
• B-CLL 20%

Medicine and Dentistry

• Diffuse Large B-Cell Lymphoma 100%
• Tumor Suppressor Protein 100%
• Allele 20%
• Disease Predisposition 20%
• Disease 20%
• Somatics 20%
• Malignant Neoplasm 20%
• Neoplasm 20%
• Cancer 20%
• Protein P53 20%
• DNA Damage Response 20%
• Mantle Cell Lymphoma 20%
• Acute Leukemia 20%
• Germline Mutation 20%
• Acute Lymphoblastic Leukemia 20%
• B-Cell Chronic Lymphocytic Leukemia 20%
• B-Cell Lymphoma 20%
• Follicular Lymphoma 20%
• Peripheral T-Cell Lymphoma 20%
• RNA Splicing 20%
• Genomic DNA 20%
• Ataxia Telangiectasia 20%
• Nonsense Mutation 20%
• Protein Serine Threonine Kinase 20%
• Prolymphocytic Leukemia 20%

Biochemistry, Genetics and Molecular Biology

• Tumor Suppressor Protein 100%
• B Cell 100%
• T Cell 28%
• Allele 14%
• Phosphotransferase 14%
• Kinase 14%
• Germline Mutation 14%
• P53 14%
• Missense 14%
• DNA Damage Response 14%
• Nonsense Mutation 14%
• Serine 14%
• Threonine 14%
• RNA Splicing 14%