TY - JOUR
T1 - Associations of Objectively Measured Physical Activity and Abdominal Fat Distribution
AU - Philipsen, Annelotte
AU - Hansen, Anne-Louise Smidt
AU - Jørgensen, Marit Eika
AU - Brage, Søren
AU - Carstensen, Bendix
AU - Sandbaek, Annelli
AU - Almdal, Thomas Peter
AU - Gram, Jeppe
AU - Pedersen, Erling Bjerregaard
AU - Lauritzen, Torsten
AU - Witte, Daniel Rinse
N1 - Medicine & Science in Sports & Exercise:
May 2015 - Volume 47 - Issue 5 - p 983–989
PY - 2015
Y1 - 2015
N2 - INTRODUCTION/PURPOSE: Visceral adipose tissue (VAT) and physical activity are both independent predictors of type 2 diabetes. Physical activity and overall obesity are inversely associated with each other. Yet the nature of the association between objectively measured dimensions of physical activity and abdominal fat distribution has not been well characterised. We aimed to do so in middle-aged to elderly population at high risk of diabetes.METHODS: A cross-sectional analysis of 1134 participants of the ADDITION-PRO study. VAT and subcutaneous adipose tissue (SAT) were assessed one-dimensionally by ultrasonography and physical activity with combined accelerometry and heart rate monitoring. Linear regression of physical activity energy expenditure (PAEE) and time spent in different physical activity intensity levels on VAT and SAT was performed.RESULTS: Median BMI was 26.6 kg/m and PAEE 28.1 kJ/kg/day, with 18.9 hours/day spent sedentary, 4.5 hours/day in light-intensity physical activity, and 0.4 hours/day in moderate-intensity physical activity. PAEE was significantly negatively associated with VAT and for women also SAT. The difference in VAT was -1.1mm (95%CI:-1.8;-0.3) per 10 kJ/kg/day increment, and the corresponding difference in SAT for women was -0.6mm (95%CI:-1.2;-0.04), in models adjusted for age, sex and waist circumference. Exchanging one hour of light physical activity with moderate physical activity was significantly associated with VAT (-4.5mm, 95%CI: -7.6;-1.5). Exchanging one sedentary hour with light physical activity was significantly associated with both VAT (-0.9mm, 95%CI: -0.1;-1.8) and SAT (-0.4mm, 95%CI: -0.0;-0.7).CONCLUSIONS: In this population with low physical activity levels, cross sectional findings indicate that increasing overall physical activity and decreasing time spent sedentary is important in order to avoid the accumulation of metabolically deleterious VAT.
AB - INTRODUCTION/PURPOSE: Visceral adipose tissue (VAT) and physical activity are both independent predictors of type 2 diabetes. Physical activity and overall obesity are inversely associated with each other. Yet the nature of the association between objectively measured dimensions of physical activity and abdominal fat distribution has not been well characterised. We aimed to do so in middle-aged to elderly population at high risk of diabetes.METHODS: A cross-sectional analysis of 1134 participants of the ADDITION-PRO study. VAT and subcutaneous adipose tissue (SAT) were assessed one-dimensionally by ultrasonography and physical activity with combined accelerometry and heart rate monitoring. Linear regression of physical activity energy expenditure (PAEE) and time spent in different physical activity intensity levels on VAT and SAT was performed.RESULTS: Median BMI was 26.6 kg/m and PAEE 28.1 kJ/kg/day, with 18.9 hours/day spent sedentary, 4.5 hours/day in light-intensity physical activity, and 0.4 hours/day in moderate-intensity physical activity. PAEE was significantly negatively associated with VAT and for women also SAT. The difference in VAT was -1.1mm (95%CI:-1.8;-0.3) per 10 kJ/kg/day increment, and the corresponding difference in SAT for women was -0.6mm (95%CI:-1.2;-0.04), in models adjusted for age, sex and waist circumference. Exchanging one hour of light physical activity with moderate physical activity was significantly associated with VAT (-4.5mm, 95%CI: -7.6;-1.5). Exchanging one sedentary hour with light physical activity was significantly associated with both VAT (-0.9mm, 95%CI: -0.1;-1.8) and SAT (-0.4mm, 95%CI: -0.0;-0.7).CONCLUSIONS: In this population with low physical activity levels, cross sectional findings indicate that increasing overall physical activity and decreasing time spent sedentary is important in order to avoid the accumulation of metabolically deleterious VAT.
U2 - 10.1249/MSS.0000000000000504
DO - 10.1249/MSS.0000000000000504
M3 - Journal article
C2 - 25207926
SN - 0195-9131
VL - 47
SP - 983
EP - 989
JO - Medicine and Science in Sports and Exercise
JF - Medicine and Science in Sports and Exercise
IS - 5
ER -