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Association of fatal myocardial infarction with past level of physical activity: a pooled analysis of cohort studies

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Harvard

Hansen, KW, Peytz, N, Blokstra, A, Bojesen, SE, Celis-Morales, C, Chrysohoou, C, Clays, E, De Bacquer, D, Galatius, S, Gray, SR, Ho, F, Kavousi, M, Koolhaas, CM, Kouvari, M, Løchen, M-L, Marques-Vidal, P, Osler, M, Panagiotakos, D, Pell, JP, Sulo, G, Tell, GS, Vassiliou, V, Verschuren, WMM & Prescott, E 2021, 'Association of fatal myocardial infarction with past level of physical activity: a pooled analysis of cohort studies', European Journal of Preventive Cardiology. https://doi.org/10.1093/eurjpc/zwaa146

APA

Hansen, K. W., Peytz, N., Blokstra, A., Bojesen, S. E., Celis-Morales, C., Chrysohoou, C., Clays, E., De Bacquer, D., Galatius, S., Gray, S. R., Ho, F., Kavousi, M., Koolhaas, C. M., Kouvari, M., Løchen, M-L., Marques-Vidal, P., Osler, M., Panagiotakos, D., Pell, J. P., ... Prescott, E. (2021). Association of fatal myocardial infarction with past level of physical activity: a pooled analysis of cohort studies. European Journal of Preventive Cardiology. https://doi.org/10.1093/eurjpc/zwaa146

CBE

Hansen KW, Peytz N, Blokstra A, Bojesen SE, Celis-Morales C, Chrysohoou C, Clays E, De Bacquer D, Galatius S, Gray SR, Ho F, Kavousi M, Koolhaas CM, Kouvari M, Løchen M-L, Marques-Vidal P, Osler M, Panagiotakos D, Pell JP, Sulo G, Tell GS, Vassiliou V, Verschuren WMM, Prescott E. 2021. Association of fatal myocardial infarction with past level of physical activity: a pooled analysis of cohort studies. European Journal of Preventive Cardiology. https://doi.org/10.1093/eurjpc/zwaa146

MLA

Vancouver

Author

Hansen, Kim Wadt ; Peytz, Nina ; Blokstra, Anneke ; Bojesen, Stig E ; Celis-Morales, Carlos ; Chrysohoou, Christina ; Clays, Els ; De Bacquer, Dirk ; Galatius, Søren ; Gray, Stuart R ; Ho, Frederick ; Kavousi, Maryam ; Koolhaas, Chantal M ; Kouvari, Matina ; Løchen, Maja-Lisa ; Marques-Vidal, Pedro ; Osler, Merete ; Panagiotakos, Demosthenes ; Pell, Jill P ; Sulo, Gerhard ; Tell, Grethe S ; Vassiliou, Vassilios ; Verschuren, W M Monique ; Prescott, Eva. / Association of fatal myocardial infarction with past level of physical activity : a pooled analysis of cohort studies. I: European Journal of Preventive Cardiology. 2021.

Bibtex

@article{073178fd7f9245aba0909f7a4ab8eca7,
title = "Association of fatal myocardial infarction with past level of physical activity: a pooled analysis of cohort studies",
abstract = "AIMS: To assess the association between past level of physical activity (PA) and risk for death during the acute phase of myocardial infarction (MI) in a pooled analysis of cohort studies.METHODS AND RESULTS: European cohorts including participants with a baseline assessment of PA, conventional cardiovascular (CV) risk factors, and available follow-up on MI and death were eligible. Patients with an incident MI were included. Leisure-time PA was grouped as sedentary (<7 MET-hours), low (7-16 MET-hours), moderate (16.1-32 MET-hours), or high (>32 MET-hours) based on calculated net weekly energy expenditure. The main outcome measures were instant and 28-day case fatality of MI. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using multivariate random-effects models. Adjustments for age, sex, CV risk factors, alcohol consumption, and socioeconomic status were made. From 10 cohorts including a total of 1 495 254 participants, 28 140 patients with an incident MI comprised the study population. A total of 4976 (17.7%) died within 28 days-of these 3101 (62.3%) were classified as instant fatal MI. Compared with sedentary individuals, those with a higher level of PA had lower adjusted odds of instant fatal MI: low PA [OR, 0.79 (95% CI, 0.60-1.04)], moderate PA [0.67 (0.51-0.89)], and high PA [0.55 (0.40-0.76)]. Similar results were found for 28-day fatal MI: low PA [0.85 (0.71-1.03)], moderate PA [0.64 (0.51-0.80)], and high PA [0.72 (0.51-1.00)]. A low-to-moderate degree of heterogeneity was detected in the analysis of instant fatal MI (I2 = 47.3%), but not in that of 28-day fatal MI (I2 = 0.0%).CONCLUSION: A moderate-to-high level of PA was associated with a lower risk of instant and 28-day death in relation to a MI.",
author = "Hansen, {Kim Wadt} and Nina Peytz and Anneke Blokstra and Bojesen, {Stig E} and Carlos Celis-Morales and Christina Chrysohoou and Els Clays and {De Bacquer}, Dirk and S{\o}ren Galatius and Gray, {Stuart R} and Frederick Ho and Maryam Kavousi and Koolhaas, {Chantal M} and Matina Kouvari and Maja-Lisa L{\o}chen and Pedro Marques-Vidal and Merete Osler and Demosthenes Panagiotakos and Pell, {Jill P} and Gerhard Sulo and Tell, {Grethe S} and Vassilios Vassiliou and Verschuren, {W M Monique} and Eva Prescott",
note = "{\textcopyright} The Author(s) 2021. Published on behalf of the European Society of Cardiology. All rights reserved. For permissions, please email: journals.permissions@oup.com.",
year = "2021",
month = feb,
day = "10",
doi = "10.1093/eurjpc/zwaa146",
language = "English",
journal = "European Journal of Preventive Cardiology",
issn = "2047-4873",
publisher = "Sage Publications Ltd",

}

RIS

TY - JOUR

T1 - Association of fatal myocardial infarction with past level of physical activity

T2 - a pooled analysis of cohort studies

AU - Hansen, Kim Wadt

AU - Peytz, Nina

AU - Blokstra, Anneke

AU - Bojesen, Stig E

AU - Celis-Morales, Carlos

AU - Chrysohoou, Christina

AU - Clays, Els

AU - De Bacquer, Dirk

AU - Galatius, Søren

AU - Gray, Stuart R

AU - Ho, Frederick

AU - Kavousi, Maryam

AU - Koolhaas, Chantal M

AU - Kouvari, Matina

AU - Løchen, Maja-Lisa

AU - Marques-Vidal, Pedro

AU - Osler, Merete

AU - Panagiotakos, Demosthenes

AU - Pell, Jill P

AU - Sulo, Gerhard

AU - Tell, Grethe S

AU - Vassiliou, Vassilios

AU - Verschuren, W M Monique

AU - Prescott, Eva

N1 - © The Author(s) 2021. Published on behalf of the European Society of Cardiology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

PY - 2021/2/10

Y1 - 2021/2/10

N2 - AIMS: To assess the association between past level of physical activity (PA) and risk for death during the acute phase of myocardial infarction (MI) in a pooled analysis of cohort studies.METHODS AND RESULTS: European cohorts including participants with a baseline assessment of PA, conventional cardiovascular (CV) risk factors, and available follow-up on MI and death were eligible. Patients with an incident MI were included. Leisure-time PA was grouped as sedentary (<7 MET-hours), low (7-16 MET-hours), moderate (16.1-32 MET-hours), or high (>32 MET-hours) based on calculated net weekly energy expenditure. The main outcome measures were instant and 28-day case fatality of MI. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using multivariate random-effects models. Adjustments for age, sex, CV risk factors, alcohol consumption, and socioeconomic status were made. From 10 cohorts including a total of 1 495 254 participants, 28 140 patients with an incident MI comprised the study population. A total of 4976 (17.7%) died within 28 days-of these 3101 (62.3%) were classified as instant fatal MI. Compared with sedentary individuals, those with a higher level of PA had lower adjusted odds of instant fatal MI: low PA [OR, 0.79 (95% CI, 0.60-1.04)], moderate PA [0.67 (0.51-0.89)], and high PA [0.55 (0.40-0.76)]. Similar results were found for 28-day fatal MI: low PA [0.85 (0.71-1.03)], moderate PA [0.64 (0.51-0.80)], and high PA [0.72 (0.51-1.00)]. A low-to-moderate degree of heterogeneity was detected in the analysis of instant fatal MI (I2 = 47.3%), but not in that of 28-day fatal MI (I2 = 0.0%).CONCLUSION: A moderate-to-high level of PA was associated with a lower risk of instant and 28-day death in relation to a MI.

AB - AIMS: To assess the association between past level of physical activity (PA) and risk for death during the acute phase of myocardial infarction (MI) in a pooled analysis of cohort studies.METHODS AND RESULTS: European cohorts including participants with a baseline assessment of PA, conventional cardiovascular (CV) risk factors, and available follow-up on MI and death were eligible. Patients with an incident MI were included. Leisure-time PA was grouped as sedentary (<7 MET-hours), low (7-16 MET-hours), moderate (16.1-32 MET-hours), or high (>32 MET-hours) based on calculated net weekly energy expenditure. The main outcome measures were instant and 28-day case fatality of MI. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using multivariate random-effects models. Adjustments for age, sex, CV risk factors, alcohol consumption, and socioeconomic status were made. From 10 cohorts including a total of 1 495 254 participants, 28 140 patients with an incident MI comprised the study population. A total of 4976 (17.7%) died within 28 days-of these 3101 (62.3%) were classified as instant fatal MI. Compared with sedentary individuals, those with a higher level of PA had lower adjusted odds of instant fatal MI: low PA [OR, 0.79 (95% CI, 0.60-1.04)], moderate PA [0.67 (0.51-0.89)], and high PA [0.55 (0.40-0.76)]. Similar results were found for 28-day fatal MI: low PA [0.85 (0.71-1.03)], moderate PA [0.64 (0.51-0.80)], and high PA [0.72 (0.51-1.00)]. A low-to-moderate degree of heterogeneity was detected in the analysis of instant fatal MI (I2 = 47.3%), but not in that of 28-day fatal MI (I2 = 0.0%).CONCLUSION: A moderate-to-high level of PA was associated with a lower risk of instant and 28-day death in relation to a MI.

U2 - 10.1093/eurjpc/zwaa146

DO - 10.1093/eurjpc/zwaa146

M3 - Journal article

C2 - 33564885

JO - European Journal of Preventive Cardiology

JF - European Journal of Preventive Cardiology

SN - 2047-4873

ER -

ID: 63844677