Association between DPP6 polymorphism and the risk of progressive multiple sclerosis in Northern and Southern Europeans

Paola Brambilla; Federica Esposito; Eva Lindstrom; Melissa Sorosina; Giacomo Giacalone; Ferdinando Clarelli; Mariaemma Rodegher; Bruno Colombo; Lucia Moiola; Angelo Ghezzi; Ruggero Capra; Laura Collimedaglia; Gabriella Coniglio; Elisabeth G Celius; Daniela Galimberti; Per Soelberg Sørensen; Vittorio Martinelli; Annette B Oturai; Hanne F Harbo; Jan Hillert; Giancarlo Comi; Filippo Martinelli-Boneschi

doi:10.1016/j.neulet.2012.10.008

Association between DPP6 polymorphism and the risk of progressive multiple sclerosis in Northern and Southern Europeans

Paola Brambilla, Federica Esposito, Eva Lindstrom, Melissa Sorosina, Giacomo Giacalone, Ferdinando Clarelli, Mariaemma Rodegher, Bruno Colombo, Lucia Moiola, Angelo Ghezzi, Ruggero Capra, Laura Collimedaglia, Gabriella Coniglio, Elisabeth G Celius, Daniela Galimberti, Per Soelberg Sørensen, Vittorio Martinelli, Annette B Oturai, Hanne F Harbo, Jan HillertGiancarlo Comi, Filippo Martinelli-Boneschi

Afdeling for Hjerne- og Nervesygdomme

16 Citationer (Scopus)

Abstrakt

In this study, we investigated the role of the dipeptidyl-peptidase-6 (DPP6) gene in the etiopathogenesis of progressive forms of multiple sclerosis (PrMS). This gene emerged as a candidate gene in a genome-wide association study (GWAS) performed in an Italian sample of PrMS and controls in which two SNPs located in the gene (rs6956703 and rs11767658) showed evidence of association (nominal p-value

Originalsprog	Engelsk
Tidsskrift	Neuroscience Letters
Vol/bind	530
Udgave nummer	2
Sider (fra-til)	155-60
Antal sider	6
ISSN	0304-3940
DOI	https://doi.org/10.1016/j.neulet.2012.10.008
Status	Udgivet - 2012

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10.1016/j.neulet.2012.10.008

Citationsformater

Brambilla, P., Esposito, F., Lindstrom, E., Sorosina, M., Giacalone, G., Clarelli, F., Rodegher, M., Colombo, B., Moiola, L., Ghezzi, A., Capra, R., Collimedaglia, L., Coniglio, G., Celius, E. G., Galimberti, D., Sørensen, P. S., Martinelli, V., Oturai, A. B., Harbo, H. F., ... Martinelli-Boneschi, F. (2012). Association between DPP6 polymorphism and the risk of progressive multiple sclerosis in Northern and Southern Europeans. Neuroscience Letters, 530(2), 155-60. https://doi.org/10.1016/j.neulet.2012.10.008

Brambilla, P, Esposito, F, Lindstrom, E, Sorosina, M, Giacalone, G, Clarelli, F, Rodegher, M, Colombo, B, Moiola, L, Ghezzi, A, Capra, R, Collimedaglia, L, Coniglio, G, Celius, EG, Galimberti, D, Sørensen, PS, Martinelli, V, Oturai, AB, Harbo, HF, Hillert, J, Comi, G & Martinelli-Boneschi, F 2012, 'Association between DPP6 polymorphism and the risk of progressive multiple sclerosis in Northern and Southern Europeans', Neuroscience Letters, bind 530, nr. 2, s. 155-60. https://doi.org/10.1016/j.neulet.2012.10.008

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title = "Association between DPP6 polymorphism and the risk of progressive multiple sclerosis in Northern and Southern Europeans",

abstract = "In this study, we investigated the role of the dipeptidyl-peptidase-6 (DPP6) gene in the etiopathogenesis of progressive forms of multiple sclerosis (PrMS). This gene emerged as a candidate gene in a genome-wide association study (GWAS) performed in an Italian sample of PrMS and controls in which two SNPs located in the gene (rs6956703 and rs11767658) showed evidence of association (nominal p-value",

author = "Paola Brambilla and Federica Esposito and Eva Lindstrom and Melissa Sorosina and Giacomo Giacalone and Ferdinando Clarelli and Mariaemma Rodegher and Bruno Colombo and Lucia Moiola and Angelo Ghezzi and Ruggero Capra and Laura Collimedaglia and Gabriella Coniglio and Celius, {Elisabeth G} and Daniela Galimberti and S{\o}rensen, {Per Soelberg} and Vittorio Martinelli and Oturai, {Annette B} and Harbo, {Hanne F} and Jan Hillert and Giancarlo Comi and Filippo Martinelli-Boneschi",

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doi = "10.1016/j.neulet.2012.10.008",

language = "English",

volume = "530",

pages = "155--60",

journal = "Neuroscience Letters",

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TY - JOUR

T1 - Association between DPP6 polymorphism and the risk of progressive multiple sclerosis in Northern and Southern Europeans

AU - Brambilla, Paola

AU - Esposito, Federica

AU - Lindstrom, Eva

AU - Sorosina, Melissa

AU - Giacalone, Giacomo

AU - Clarelli, Ferdinando

AU - Rodegher, Mariaemma

AU - Colombo, Bruno

AU - Moiola, Lucia

AU - Ghezzi, Angelo

AU - Capra, Ruggero

AU - Collimedaglia, Laura

AU - Coniglio, Gabriella

AU - Celius, Elisabeth G

AU - Galimberti, Daniela

AU - Sørensen, Per Soelberg

AU - Martinelli, Vittorio

AU - Oturai, Annette B

AU - Harbo, Hanne F

AU - Hillert, Jan

AU - Comi, Giancarlo

AU - Martinelli-Boneschi, Filippo

PY - 2012

Y1 - 2012

N2 - In this study, we investigated the role of the dipeptidyl-peptidase-6 (DPP6) gene in the etiopathogenesis of progressive forms of multiple sclerosis (PrMS). This gene emerged as a candidate gene in a genome-wide association study (GWAS) performed in an Italian sample of PrMS and controls in which two SNPs located in the gene (rs6956703 and rs11767658) showed evidence of association (nominal p-value

AB - In this study, we investigated the role of the dipeptidyl-peptidase-6 (DPP6) gene in the etiopathogenesis of progressive forms of multiple sclerosis (PrMS). This gene emerged as a candidate gene in a genome-wide association study (GWAS) performed in an Italian sample of PrMS and controls in which two SNPs located in the gene (rs6956703 and rs11767658) showed evidence of association (nominal p-value

U2 - 10.1016/j.neulet.2012.10.008

DO - 10.1016/j.neulet.2012.10.008

M3 - Journal article

C2 - 23069673

VL - 530

SP - 155

EP - 160

JO - Neuroscience Letters

JF - Neuroscience Letters

SN - 0304-3940

IS - 2

ER -

Association between DPP6 polymorphism and the risk of progressive multiple sclerosis in Northern and Southern Europeans

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