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Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Association between age, IL-10, IFNγ, stimulated C-peptide and disease progression in children with newly diagnosed Type 1 diabetes

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Vis graf over relationer
Aims:  The relation of disease progression and age, serum interleukin 10 (IL-10) and interferon gamma (IFNγ) and their genetic correlates were studied in paediatric patients with newly diagnosed Type 1 diabetes. Methods:  Two hundred and twenty-seven patients from the Hvidoere Study Group were classified in four different progression groups as assessed by change in stimulated C-peptide from 1 to 6 months. CA repeat variants of the IL-10 and IFNγ gene were genotyped and serum levels of IL-10 and IFNγ were measured at 1, 6 and 12 months. Results:  IL-10 decreased (P 
OriginalsprogEngelsk
TidsskriftDiabetic Medicine
Vol/bind29
Udgave nummer6
Sider (fra-til)734-741
Antal sider8
ISSN0742-3071
DOI
StatusUdgivet - 2012

ID: 34783259