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Region Hovedstaden - en del af Københavns Universitetshospital

Appraisal of Candidate Instruments for Assessment of the Physical Function Domain in Patients with Psoriatic Arthritis

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review


  • Ying Ying Leung
  • Ana-Maria Orbai
  • Alexis Ogdie
  • Pil Hojgaard
  • Richard Holland
  • Niti Goel
  • Jeffrey Chau
  • Laura C Coates
  • Vibeke Strand
  • Dafna D Gladman
  • Philip J Mease
  • Robin Christensen
  • William Tillett
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OBJECTIVE: Numerous patient-reported outcome measures (PROM) exist for the measurement of physical function for psoriatic arthritis (PsA), but only a few are validated comprehensively. The objective of this project was to prioritize PROM for measuring physical function for potential incorporation into a standardized outcome measurement set for PsA.

METHODS: A working group of 13 members including 2 patient research partners was formed. PROM measuring physical function in PsA were identified through a systematic literature review and recommendations by the working group. The rationale for inclusion and exclusion from the original list of existing PROM was thoroughly discussed and 2 rounds of Delphi exercises were conducted to achieve consensus.

RESULTS: Twelve PROM were reviewed and discussed. Six PROM were prioritized: Health Assessment Questionnaire (HAQ) and 4 modifications (HAQ-Disability Index, HAQ-Spondyloarthritis, modified HAQ, multidimensional HAQ), Medical Outcomes Study 36-item Short Form survey physical functioning domain, and the Patient-Reported Outcomes Measurement Information System (PROMIS) physical functioning module.

CONCLUSION: Through discussion and Delphi exercises, we achieved consensus to prioritize 6 physical function PROM for PsA. These 6 PROM will undergo further appraisal using the Outcome Measures in Rheumatology (OMERACT) Filter 2.1.

TidsskriftJournal of Rheumatology
Udgave nummer1
Sider (fra-til)58-66
Antal sider9
StatusUdgivet - 1 jan. 2021

ID: 65749086