Application of lipidomics and metabolomics to the study of adipose tissue

Ismo Mattila, Tuulikki Seppänen-Laakso, Tapani Suortti, Matej Oresic

13 Citationer (Scopus)

Abstract

Role of specific reactive lipids as well as amino acids in control of insulin signalling in adipose tissue is well recognized. Since it is practically impossible to measure the levels of all metabolites in the biological sample simultaneously with a single analytical platform, we utilize multiple platforms to study the lipids and metabolites of relevance to adipose tissue metabolism and insulin signalling. Two screening platforms cover a broad range of lipid molecular species (UPLC/MS based lipidomics platform) as well as organic acids and sterols (GCxGC-TOF platform). A targeted platform for amino acids (UPLC) is also applied.

OriginalsprogEngelsk
TidsskriftMethods in molecular biology
Vol/bind456
Sider (fra-til)123-30
Antal sider8
ISSN1064-3745
DOI
StatusUdgivet - 2008
Udgivet eksterntJa

Fingeraftryk

Dyk ned i forskningsemnerne om 'Application of lipidomics and metabolomics to the study of adipose tissue'. Sammen danner de et unikt fingeraftryk.

Citationsformater