Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Antisecretory therapy with no improvement in functional level in Ménière's disease

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Nordic results of cochlear implantation in adults: speech perception and patient reported outcomes

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Development of depression in patients with oral cavity cancer: a systematic review

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  3. Association between head and neck cancer and sexually transmitted diseases: a Danish nationwide, case-control study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Functional Loss After Meningitis-Evaluation of Vestibular Function in Patients With Postmeningitic Hearing Loss

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Reposition Chair Treatment Improves Subjective Outcomes in Refractory Benign Paroxysmal Positional Vertigo

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Superior Canal Dehiscence Surgery Outcomes Following Failed Round Window Surgery

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Benign paroksysmal positionel vertigo som komplikation ved hovedtraume

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

Conclusion Antisecretory factor-inducing (AF) specially processed cereals (SPC) were not shown to significantly improve the functional level in patients with MD. Objectives The aim of this study was to evaluate the effect of AF-inducing SPC in patients suffering from Ménière's disease (MD). Methods A randomized double-blinded, placebo-controlled cross-over study was conducted. All patients had a 2 months intake of SPC and control cereal with a 2 months washout period in between. The severity of MD was classified according to the American Academy of Otolaryngology-Head and Neck Surgery (AOO-HNS) functional scale, and the frequency of attacks was registered. Results Thirty-two patients completed the study. No carryover effect was found. In both functional level and frequency of attacks no significant effect of SPC was found. Seventeen patients showed improvement in functional level when treated with SPC (mean improvement = 0.9 points) and 14 when treated with placebo (mean improvements = 0.7 points). No patients showed worsening in functional level during treatment with SPC, but three showed worsening when treated with placebo. Seventeen patients reported fewer attacks when treated with SPC, and 22 when treated with placebo. Three patients reported more frequent attacks when treated with SPC, and three when treated with placebo. A non-parametric comparison and a parametric analysis supported the findings.

OriginalsprogEngelsk
TidsskriftActa Oto-Laryngologica
Vol/bind136
Udgave nummer3
Sider (fra-til)232-235
Antal sider4
ISSN0001-6489
DOI
StatusUdgivet - 4 dec. 2016

ID: 46001375