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Antibodies to Epstein-Barr virus and neurotropic viruses in multiple sclerosis and optic neuritis

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Harvard

Houen, G, Heiden, J, Trier, NH, Draborg, AH, Benros, ME, Zinkevičiūtė, R, Petraitytė-Burneikienė, R, Ciplys, E, Slibinskas, R & Frederiksen, JL 2021, 'Antibodies to Epstein-Barr virus and neurotropic viruses in multiple sclerosis and optic neuritis', Journal of Neuroimmunology, bind 346, 577314, s. 577314. https://doi.org/10.1016/j.jneuroim.2020.577314

APA

Houen, G., Heiden, J., Trier, N. H., Draborg, A. H., Benros, M. E., Zinkevičiūtė, R., Petraitytė-Burneikienė, R., Ciplys, E., Slibinskas, R., & Frederiksen, J. L. (2021). Antibodies to Epstein-Barr virus and neurotropic viruses in multiple sclerosis and optic neuritis. Journal of Neuroimmunology, 346, 577314. [577314]. https://doi.org/10.1016/j.jneuroim.2020.577314

CBE

Houen G, Heiden J, Trier NH, Draborg AH, Benros ME, Zinkevičiūtė R, Petraitytė-Burneikienė R, Ciplys E, Slibinskas R, Frederiksen JL. 2021. Antibodies to Epstein-Barr virus and neurotropic viruses in multiple sclerosis and optic neuritis. Journal of Neuroimmunology. 346:577314. https://doi.org/10.1016/j.jneuroim.2020.577314

MLA

Vancouver

Author

Houen, Gunnar ; Heiden, Julie ; Trier, Nicole H ; Draborg, Anette H ; Benros, Michael E ; Zinkevičiūtė, Rūta ; Petraitytė-Burneikienė, Rasa ; Ciplys, Evaldas ; Slibinskas, Rimantas ; Frederiksen, Jette L. / Antibodies to Epstein-Barr virus and neurotropic viruses in multiple sclerosis and optic neuritis. I: Journal of Neuroimmunology. 2021 ; Bind 346. s. 577314.

Bibtex

@article{66874fb6419247b6abca5f812c63de99,
title = "Antibodies to Epstein-Barr virus and neurotropic viruses in multiple sclerosis and optic neuritis",
abstract = "Antibody indices to Measles, Mumps, Varicella Zoster (MRZ) are of diagnostic value in multiple sclerosis (MS). Here, we have investigated, if this panel could be extended to increase diagnostic value. Samples from relapsing-remitting (RR) MS and optic neuritis (ON) patients were tested for reactivity to antigens from Epstein-Barr, Varicella Zoster, Measles, Mumps and Rubella (EMMRZ) viruses. Increased IgG levels in serum and cerebrospinal fluid (CSF) were found in RRMS patients, along with a significant correlation between serum and CSF. The sensitivity of the EMMRZ panel was increased approximately 40% compared to the MRZ panel, suggesting that the EMMRZ panel may be useful in MS and ON diagnostics.",
keywords = "Epstein Barr virus, Multiple sclerosis, Neurotrophic virus, Optic neuritis, Virus antigens",
author = "Gunnar Houen and Julie Heiden and Trier, {Nicole H} and Draborg, {Anette H} and Benros, {Michael E} and Rūta Zinkevi{\v c}iūtė and Rasa Petraitytė-Burneikienė and Evaldas Ciplys and Rimantas Slibinskas and Frederiksen, {Jette L}",
note = "Copyright {\textcopyright} 2020 Elsevier B.V. All rights reserved.",
year = "2021",
doi = "10.1016/j.jneuroim.2020.577314",
language = "English",
volume = "346",
pages = "577314",
journal = "Journal of Neuroimmunology",
issn = "0165-5728",
publisher = "Elsevier BV",

}

RIS

TY - JOUR

T1 - Antibodies to Epstein-Barr virus and neurotropic viruses in multiple sclerosis and optic neuritis

AU - Houen, Gunnar

AU - Heiden, Julie

AU - Trier, Nicole H

AU - Draborg, Anette H

AU - Benros, Michael E

AU - Zinkevičiūtė, Rūta

AU - Petraitytė-Burneikienė, Rasa

AU - Ciplys, Evaldas

AU - Slibinskas, Rimantas

AU - Frederiksen, Jette L

N1 - Copyright © 2020 Elsevier B.V. All rights reserved.

PY - 2021

Y1 - 2021

N2 - Antibody indices to Measles, Mumps, Varicella Zoster (MRZ) are of diagnostic value in multiple sclerosis (MS). Here, we have investigated, if this panel could be extended to increase diagnostic value. Samples from relapsing-remitting (RR) MS and optic neuritis (ON) patients were tested for reactivity to antigens from Epstein-Barr, Varicella Zoster, Measles, Mumps and Rubella (EMMRZ) viruses. Increased IgG levels in serum and cerebrospinal fluid (CSF) were found in RRMS patients, along with a significant correlation between serum and CSF. The sensitivity of the EMMRZ panel was increased approximately 40% compared to the MRZ panel, suggesting that the EMMRZ panel may be useful in MS and ON diagnostics.

AB - Antibody indices to Measles, Mumps, Varicella Zoster (MRZ) are of diagnostic value in multiple sclerosis (MS). Here, we have investigated, if this panel could be extended to increase diagnostic value. Samples from relapsing-remitting (RR) MS and optic neuritis (ON) patients were tested for reactivity to antigens from Epstein-Barr, Varicella Zoster, Measles, Mumps and Rubella (EMMRZ) viruses. Increased IgG levels in serum and cerebrospinal fluid (CSF) were found in RRMS patients, along with a significant correlation between serum and CSF. The sensitivity of the EMMRZ panel was increased approximately 40% compared to the MRZ panel, suggesting that the EMMRZ panel may be useful in MS and ON diagnostics.

KW - Epstein Barr virus

KW - Multiple sclerosis

KW - Neurotrophic virus

KW - Optic neuritis

KW - Virus antigens

U2 - 10.1016/j.jneuroim.2020.577314

DO - 10.1016/j.jneuroim.2020.577314

M3 - Journal article

C2 - 32682138

VL - 346

SP - 577314

JO - Journal of Neuroimmunology

JF - Journal of Neuroimmunology

SN - 0165-5728

M1 - 577314

ER -

ID: 60407158