TY - JOUR
T1 - An international study of the quality of life of adult patients treated with home parenteral nutrition
AU - Baxter, Janet P
AU - Fayers, Peter M
AU - Bozzetti, Federico
AU - Kelly, Darlene
AU - Joly, Francisca
AU - Wanten, Geert
AU - Jonkers, Cora
AU - Cuerda, Cristina
AU - van Gossum, Andre
AU - Klek, Stanislaw
AU - Boudreault, Marie-France
AU - Gilbert, Alain
AU - Jobin, Manon
AU - Staun, Michael
AU - Gillanders, Lyn
AU - Forbes, Alastair
AU - O'Callaghan, Margie
AU - Faedo, Ceferino Martínez
AU - Brunelli, Cinzia
AU - Mariani, Luigi
AU - Pironi, Loris
AU - Home Artificial Nutrition and Chronic Intestinal Failure Special Interest Group of the European Society for Clinical Nutrition and Metabolism (ESPEN)
N1 - Copyright © 2018 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.
PY - 2019/8/1
Y1 - 2019/8/1
N2 - BACKGROUND & AIMS: Home parenteral nutrition-quality of life (HPN-QOL©) is a self-assessment tool for the measurement of QOL in patients on HPN. The aims of this study were: to re-assess the basic psychometric properties of the HPN-QOL© in a multinational sample of adult patients; to provide a description of QOL dimensions by short and long HPN treatment duration; to explore clinical factors potentially associated to QOL scores.METHODS: Patients (n = 699) from 14 countries completed the HPN-QOL©. The questionnaires were analysed to evaluate data completeness, convergent/discriminant validity and internal-consistency reliability. The association of overall QOL and HPN treatment duration as well as other clinical factors were investigated using multivariable linear regression models.RESULTS: The analysis of the multitrait-scaling and internal consistency indicates a good fit with the questionnaire structure for most items. Item discriminant validity correlation was satisfactory and psychometric evaluation of the HPN-QOL© in the different English, French and Italian language patient sub-groups confirmed psychometric equivalence of the three questionnaire versions. The results of the multivariable linear regression showed that QOL scores were significantly associated with HPN duration (better in long-term), underlying disease (better in Crohn's disease and mesenteric ischaemia) and living status (worse in living alone) and, after adjusting for the other factors, with the number of days of HPN infusion per week.CONCLUSIONS: The HPN-QOL©, is a valid tool for measurement of QOL in patients on HPN, to be used in the clinical practice as well as in research.
AB - BACKGROUND & AIMS: Home parenteral nutrition-quality of life (HPN-QOL©) is a self-assessment tool for the measurement of QOL in patients on HPN. The aims of this study were: to re-assess the basic psychometric properties of the HPN-QOL© in a multinational sample of adult patients; to provide a description of QOL dimensions by short and long HPN treatment duration; to explore clinical factors potentially associated to QOL scores.METHODS: Patients (n = 699) from 14 countries completed the HPN-QOL©. The questionnaires were analysed to evaluate data completeness, convergent/discriminant validity and internal-consistency reliability. The association of overall QOL and HPN treatment duration as well as other clinical factors were investigated using multivariable linear regression models.RESULTS: The analysis of the multitrait-scaling and internal consistency indicates a good fit with the questionnaire structure for most items. Item discriminant validity correlation was satisfactory and psychometric evaluation of the HPN-QOL© in the different English, French and Italian language patient sub-groups confirmed psychometric equivalence of the three questionnaire versions. The results of the multivariable linear regression showed that QOL scores were significantly associated with HPN duration (better in long-term), underlying disease (better in Crohn's disease and mesenteric ischaemia) and living status (worse in living alone) and, after adjusting for the other factors, with the number of days of HPN infusion per week.CONCLUSIONS: The HPN-QOL©, is a valid tool for measurement of QOL in patients on HPN, to be used in the clinical practice as well as in research.
KW - Home parenteral nutrition
KW - Intestinal failure
KW - Patient reported outcomes
KW - Quality of life
UR - http://www.scopus.com/inward/record.url?scp=85051406224&partnerID=8YFLogxK
U2 - 10.1016/j.clnu.2018.07.024
DO - 10.1016/j.clnu.2018.07.024
M3 - Journal article
C2 - 30115461
SN - 0261-5614
VL - 38
SP - 1788
EP - 1796
JO - Clinical nutrition (Edinburgh, Scotland)
JF - Clinical nutrition (Edinburgh, Scotland)
IS - 4
ER -